Proadifen hydrochloride structure
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Common Name | Proadifen hydrochloride | ||
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CAS Number | 62-68-0 | Molecular Weight | 389.959 | |
Density | N/A | Boiling Point | 460.8ºC at 760 mmHg | |
Molecular Formula | C23H32ClNO2 | Melting Point | 122-123ºC | |
MSDS | Chinese USA | Flash Point | 132.3ºC |
Use of Proadifen hydrochlorideProadifen hydrochloride is a Cytochrome P450 inhibitor (IC50 = 19μM). IC50 value: 19μMTarget: P450Proadifen HCl has many biochemical functions, some of which include: inhibitory effects on NOS1 (neuronal nitric oxide synthase; IC50 = 90 mM), adult mouse skeletal muscle AChR (acetyl choline receptor), hepatic drug metabolism via the CYP (cytochrome P450) system, CYP-dependent (cytochrome P450-dependent) arachidonate metabolism (90% at 50 μM), transmembrane calcium influx, and platelet thromboxane synthesis. This compound has also been shown to block KIR6.1 (ATP-sensitive inward rectifier potassium channel 8; IC50 = 4.4 mM) and stimulate endothelial cell prostacyclin production. |
Name | 2-(diethylamino)ethyl 2,2-diphenylpentanoate,hydrochloride |
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Synonym | More Synonyms |
Description | Proadifen hydrochloride is a Cytochrome P450 inhibitor (IC50 = 19μM). IC50 value: 19μMTarget: P450Proadifen HCl has many biochemical functions, some of which include: inhibitory effects on NOS1 (neuronal nitric oxide synthase; IC50 = 90 mM), adult mouse skeletal muscle AChR (acetyl choline receptor), hepatic drug metabolism via the CYP (cytochrome P450) system, CYP-dependent (cytochrome P450-dependent) arachidonate metabolism (90% at 50 μM), transmembrane calcium influx, and platelet thromboxane synthesis. This compound has also been shown to block KIR6.1 (ATP-sensitive inward rectifier potassium channel 8; IC50 = 4.4 mM) and stimulate endothelial cell prostacyclin production. |
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Related Catalog |
Boiling Point | 460.8ºC at 760 mmHg |
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Melting Point | 122-123ºC |
Molecular Formula | C23H32ClNO2 |
Molecular Weight | 389.959 |
Flash Point | 132.3ºC |
Exact Mass | 389.212158 |
PSA | 29.54000 |
LogP | 5.45980 |
Storage condition | −20°C |
Stability | Store in Freezer |
Water Solubility | Soluble in methanol or water |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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