Ethylthiourea

Modify Date: 2024-01-11 16:10:57

Ethylthiourea Structure
Ethylthiourea structure
Common Name Ethylthiourea
CAS Number 625-53-6 Molecular Weight 104.174
Density 1.1±0.1 g/cm3 Boiling Point 161.6±23.0 °C at 760 mmHg
Molecular Formula C3H8N2S Melting Point 108-110 °C(lit.)
MSDS Chinese USA Flash Point 51.5±22.6 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name ethylthiourea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 161.6±23.0 °C at 760 mmHg
Melting Point 108-110 °C(lit.)
Molecular Formula C3H8N2S
Molecular Weight 104.174
Flash Point 51.5±22.6 °C
Exact Mass 104.040817
PSA 70.14000
LogP -0.18
Vapour Pressure 2.3±0.3 mmHg at 25°C
Index of Refraction 1.549
Storage condition Store at RT

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YT3700000
CHEMICAL NAME :
Urea, 1-ethyl-2-thio-
CAS REGISTRY NUMBER :
625-53-6
BEILSTEIN REFERENCE NO. :
1699551
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C3-H8-N2-S
MOLECULAR WEIGHT :
104.19
WISWESSER LINE NOTATION :
SUYZM2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
500 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1 gm/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - gastrointestinal system Reproductive - Specific Developmental Abnormalities - urogenital system

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
10 mg/plate
REFERENCE :
BIZNAT Biologisches Zentralblatt. (VEB Georg Thieme, Postfach 946, Leipzig DDR-7010, Ger. Dem. Rep.) V.1- 1881- Volume(issue)/page/year: 95,463,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4672 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1031 (estimated) No. of Female Employees: 449 (estimated)

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases 25
Safety Phrases S36/37/39-S45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS YT3700000
Packaging Group III
Hazard Class 6.1

 Synthetic Route

 Articles5

More Articles
Structural and spectroscopic studies of some adducts of silver(I) halides with thiourea and N-ethyl substituted thioureas.

Dalton Trans. 39(18) , 4391-404, (2010)

Syntheses, single crystal X-ray structural and spectroscopic characterizations are described for a variety of adducts of silver halides with thiourea ('tu'), N-ethylthiourea ('ettu' = EtNH.CS.NH(2)) a...

Infrared spectra of new Re(III) complexes with thiourea derivatives.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 58(14) , 3085-92, (2002)

Complexes of the type [Re(III)L6]X3, with L = thiourea, N-methylthiourea, N-ethylthiourea or N,N'-dimethytlthiourea and X = Cl- or PF6-, were prepared as suitable precursors for the synthesis of new r...

A convenient protocol for selective cleavage of 2-hydroxy acid amides. Application to semisynthesis of the cyclic heptapeptide aza HUN-7293.

J. Org. Chem. 67(24) , 8299-304, (2002)

A two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides has been developed. Mesylation of the model substrate 2-(hydroxypropionylamino)-4-methylpentanoic acid methyl ester (...

 Synonyms

Urea,1-ethyl-2-thio
Ethylthiourea
MFCD00004939
methanethiol, 1-(ethylamino)-1-imino-
N-Ethylcarbamimidothioic acid
Thiourea,ethyl
N-Ethylthiocarbamide
N-ETHYLTHIOUREA
Thiourea,N-ethyl
Ethyl-2-thiourea
1-ethyl-2-thiourea
EINECS 210-899-3
1-Ethylthiourea
ethyl thiourea
Thiourea, N-ethyl-
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