Rhodamine 123

Modify Date: 2024-01-02 15:20:44

Rhodamine 123 Structure
Rhodamine 123 structure
 Common Name Rhodamine 123
CAS Number 62669-70-9 Molecular Weight 380.824
Density N/A Boiling Point N/A
Molecular Formula C21H17ClN2O3 Melting Point 235 °C
MSDS Chinese USA Flash Point N/A

 Use of Rhodamine 123


Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm).

 Names

Name rhodamine 123
Synonym More Synonyms

 Rhodamine 123 Biological Activity

Description Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm).
Related Catalog
In Vitro The intensity of R123 fluorescence has a peak at concentration of 50 μM, and decreases to zero at higher concentrations due to self-quenching[1].
Kinase Assay Measurements are made at room temperature with continuous stirring of the mitochondrial suspension using spectrophotometer equipped with a magnetic stirrer with fluorescent cation R123 as probe. Excitation and emission wavelengths are 503 nm and 527 nm, respectively. The incubation medium is the respiration buffer. R123 and sodium pyruvate are added to final concentrations of 50 nM and 10 mM, respectively. Isolated mitochondria maintain a steady membrane potential (±5%) throughout the duration of the recording[1].
References

[1]. M. Huang, et al. Mitochondrial Inner Membrane Electrophysiology Assessed by Rhodamine-123 Transport and Fluorescence. Ann Biomed Eng. 2007 Jul; 35(7): 1276–1285.

 Chemical & Physical Properties

Melting Point 235 °C
Molecular Formula C21H17ClN2O3
Molecular Weight 380.824
Exact Mass 380.092773
PSA 89.31000
LogP 5.53580
Water Solubility Partially soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE0883000
CHEMICAL NAME :
Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
CAS REGISTRY NUMBER :
62669-70-9
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C21-H17-N2-O3.Cl
MOLECULAR WEIGHT :
380.85

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
60 mg/kg
SEX/DURATION :
female 7-10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 9,29,1989
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
60 mg/kg
SEX/DURATION :
female 7-10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 40,143,1989

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS ZE0883000
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

RHODAMINE METHYL ESTER CHLORIDE
Xanthylium, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-, chloride (1:1)
2-(6-amino-3-imino-3H-xanthen-9-yl)-methyl ester,hydrochloride
rh123
3,6-Diamino-9-[2-(methoxycarbonyl)phenyl]xanthenium chloride
MFCD00012664
RHODAMINE 123 HYDROCHLORIDE
Rhodamine 123
RHODAMINE 123,PURE
XANTHYLIUM, 3,6-DIAMINO-9-(2-(METHOXYCARBONYL)PHENYL)-, CHLORIDE
rhodamine 110 methyl ester
Rhodamine-123
EINECS 263-687-8
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Related Compounds: More...
Dihydrorhodamine 123
109244-58-8
rhodamine 123 hydrate
207671-45-2
tetrabromorhodamine 123
83796-96-7
Iododihydrorhodamine 123
109244-59-9
2'-iododihydrorhodamine 123
109282-63-5
Tetrabromorhodamine 123 bromide
623903-26-4
2',7'-diiododihydrorhodamine 123
109244-60-2
4',7'-diiododihydrorhodamine 123
109244-61-3
2',4',7'-triiododihydrorhodamine 123
109244-62-4
Chemsrc provides Rhodamine 123(CAS#:62669-70-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Rhodamine 123 are included as well.>> amp version: Rhodamine 123

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