4-Amino-N-methylbenzamide

Modify Date: 2026-07-03 17:35:21

4-Amino-N-methylbenzamide Structure
4-Amino-N-methylbenzamide structure
Common Name 4-Amino-N-methylbenzamide
CAS Number 6274-22-2 Molecular Weight 150.178
Density 1.1±0.1 g/cm3 Boiling Point 364.1±25.0 °C at 760 mmHg
Molecular Formula C8H10N2O Melting Point 181 °C
MSDS USA Flash Point 174.0±23.2 °C

 Names

Name 4-Amino-N-methylbenzamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 364.1±25.0 °C at 760 mmHg
Melting Point 181 °C
Molecular Formula C8H10N2O
Molecular Weight 150.178
Flash Point 174.0±23.2 °C
Exact Mass 150.079315
PSA 55.12000
LogP -0.03
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.583
InChIKey XAGFYNSCWICYPA-UHFFFAOYSA-N
SMILES CNC(=O)c1ccc(N)cc1

 Safety Information

Hazard Codes Xi

 Synthetic Route

~85%

4-Amino-N-methylbenzamide Structure

4-Amino-N-methy...

CAS#:6274-22-2

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Literature: US2009/239848 A1, ; Page/Page column 24 ; US 20090239848 A1

~82%

4-Amino-N-methylbenzamide Structure

4-Amino-N-methy...

CAS#:6274-22-2

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Literature: Tetrahedron Letters, , vol. 41, # 25 p. 4933 - 4936

~%

4-Amino-N-methylbenzamide Structure

4-Amino-N-methy...

CAS#:6274-22-2

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Literature: Journal of Medicinal Chemistry, , vol. 27, # 6 p. 779 - 782

~51%

4-Amino-N-methylbenzamide Structure

4-Amino-N-methy...

CAS#:6274-22-2

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Literature: Synlett, , # 11 p. 1597 - 1601

 4-Amino-N-methylbenzamideBioassay

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Name: Anticonvulsant activity against MES (maximal electroshock) induced seizure in mice at...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL732042
Name: Competitive inhibition of Escherichia coli B H2-pteroate synthetase assessed as decre...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3280532
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Evaluated for toxicity by using rotarod test at in mice 30 min; - = No activity at 60...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL744975
Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
Name: Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL5346746
Name: Anticonvulsant activity against scMet (subcutaneous metrazole) induced seizure in mic...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL734050
Name: Anticonvulsant activity against scMet (subcutaneous metrazole) induced seizure in mic...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL729120
Name: Anticonvulsant activity against MES (maximal electroshock) induced seizure in mice at...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL732401
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 Synonyms

4-Amino-N-methyl-benzamide
4-Amino-N-methylbenzamide
4-Amino-benzoesaeure-methylamid
N-methyl-p-aminobenzamide
4-(methylcarbamoyl)aniline
4-Amino-N-methyl-benzamid
4-Aminobenzoylmethylamide
(4-aminophenyl)-N-methylcarboxamide
MFCD00665792
4-amino-benzoic acid methylamide
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