2-(2-Chloroethoxy)ethanol

Modify Date: 2026-07-02 10:14:21

2-(2-Chloroethoxy)ethanol Structure
2-(2-Chloroethoxy)ethanol structure
Common Name 2-(2-Chloroethoxy)ethanol
CAS Number 628-89-7 Molecular Weight 124.566
Density 1.1±0.1 g/cm3 Boiling Point 182.5±0.0 °C at 760 mmHg
Molecular Formula C4H9ClO2 Melting Point N/A
MSDS Chinese USA Flash Point 90.6±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-(2-Chloroethoxy)ethanol
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.1±0.1 g/cm3
Boiling Point 182.5±0.0 °C at 760 mmHg
Molecular Formula C4H9ClO2
Molecular Weight 124.566
Flash Point 90.6±0.0 °C
Exact Mass 124.029106
PSA 29.46000
LogP -0.16
Vapour Pressure 0.2±0.7 mmHg at 25°C
Index of Refraction 1.436
InChIKey LECMBPWEOVZHKN-UHFFFAOYSA-N
SMILES OCCOCCCl
Storage condition 2-8°C
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility SOLUBLE

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KK1350000
CHEMICAL NAME :
Ethanol, 2-(2-chloroethoxy)-
CAS REGISTRY NUMBER :
628-89-7
BEILSTEIN REFERENCE NO. :
0506015
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-Cl-O2
MOLECULAR WEIGHT :
124.58
WISWESSER LINE NOTATION :
QZO2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36
Safety Phrases S26-S36-S39
RIDADR UN 3334
WGK Germany 2
RTECS KK1350000
HS Code 2909499000

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles3

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

GC method for quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) and N-methyl-2-pyrrolidinone (NMP) in quetiapine.

Acta Pol. Pharm. 64(2) , 187-9, (2007)

Nitrophenyl-EGTA, a photolabile chelator that selectively binds Ca2+ with high affinity and releases it rapidly upon photolysis.

Proc. Natl. Acad. Sci. U. S. A. 91(1) , 187-91, (1994)

The synthesis and properties of a caged calcium are described. The compound is an ortho-nitrophenyl derivative of EGTA. It is synthesized in 10 steps and with 24% overall yield. The photosensitive che...

One-Pot Synthesis of Well-Defined Amphiphilic and Adaptative Block Copolymers via Versatile Combination of “Click” Chemistry and ATRP. Mespouille L, et al.

Macromol. Rapid Commun. 28(22) , 2151-58, (2007)

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Diglycol Ch
2-(2-chloroethoxy)-ethano
2-CHLOROETHOXYETHANOL
2-(2-Chloroethoxy)ethanol
2-(2-hydroxyethoxy)ethyl chloride
Diglycol chlorhydrin
chloroethoxyethanol
DEGCH
2-(2-chloroethoxy)-1-ethanol
EINECS 211-059-9
ethylene glycol mono-2-chloroethyl ether
2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-8-(BOC)-2,8-DIAZASPIRO[4.5]DECANE-3-CARBOXYLIC ACID
2-(2-chloroethoxy)-ethanol
MFCD00002870
2-(2-Cloroethoxy)Ethanol
Diglycolchlorohydrin

 2-(2-Chloroethoxy)ethanol | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the downstream products of 2-(2-Chloroethoxy)ethanol?
A: Related downstream products(CAS) of 2-(2-Chloroethoxy)ethanol: 104568-29-8;104568-24-3;3733-63-9;14258-40-3;929-06-6;299167-98-9;2192-20-3;127441-50-3;139115-90-5;111-44-4.
Q: What are the upstream materials of 2-(2-Chloroethoxy)ethanol?
A: Related upstream materials(CAS) of 2-(2-Chloroethoxy)ethanol: 75-21-8;107-07-3;111-46-6;14258-40-3;123-91-1;2568-30-1;107-21-1;111-44-4;7664-93-9.
Q: What is the CAS number of 2-(2-Chloroethoxy)ethanol?
A: CAS number of 2-(2-Chloroethoxy)ethanol is 628-89-7.
Q: What is the SMILES notation of 2-(2-Chloroethoxy)ethanol?
A: SMILES notation of 2-(2-Chloroethoxy)ethanol is OCCOCCCl.
Q: What is the boiling point of 2-(2-Chloroethoxy)ethanol?
A: Boiling point of 2-(2-Chloroethoxy)ethanol is 182.5±0.0 °C at 760 mmHg.
Q: How is the water solubility of 2-(2-Chloroethoxy)ethanol?
A: Water solubility of 2-(2-Chloroethoxy)ethanol: SOLUBLE.
Q: What is the molecular weight of 2-(2-Chloroethoxy)ethanol?
A: Molecular weight of 2-(2-Chloroethoxy)ethanol is 124.566.
Q: What is the LogP of 2-(2-Chloroethoxy)ethanol?
A: LogP of 2-(2-Chloroethoxy)ethanol is -0.16.
Q: What is the molecular formula of 2-(2-Chloroethoxy)ethanol?
A: Molecular formula of 2-(2-Chloroethoxy)ethanol is C4H9ClO2.
Q: What are the storage conditions for 2-(2-Chloroethoxy)ethanol?
A: Storage conditions for 2-(2-Chloroethoxy)ethanol: 2-8°C.

 2-(2-Chloroethoxy)ethanolfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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