Diglycolamine

Modify Date: 2024-01-02 16:29:18

Diglycolamine Structure
Diglycolamine structure
Common Name Diglycolamine
CAS Number 929-06-6 Molecular Weight 105.136
Density 1.0±0.1 g/cm3 Boiling Point 221.0±0.0 °C at 760 mmHg
Molecular Formula C4H11NO2 Melting Point -12.5 °C
MSDS Chinese USA Flash Point 76.6±20.4 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Use of Diglycolamine


Amino-PEG2-alcohol is a PEG derivative containing an amino group with a hydroxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

 Names

Name 2-(2-Aminoethoxy)ethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 221.0±0.0 °C at 760 mmHg
Melting Point -12.5 °C
Molecular Formula C4H11NO2
Molecular Weight 105.136
Flash Point 76.6±20.4 °C
Exact Mass 105.078979
PSA 55.48000
LogP -1.37
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.449
Stability Stable. Incompatible with acids, strong oxidizing agents. Reacts with carbon dioxide.
Water Solubility miscible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KJ6125000
CHEMICAL NAME :
Ethanol, 2-(2-aminoethoxy)-
CAS REGISTRY NUMBER :
929-06-6
BEILSTEIN REFERENCE NO. :
0906728
LAST UPDATED :
199806
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C4-H11-N-O2
MOLECULAR WEIGHT :
105.16
WISWESSER LINE NOTATION :
Z2O2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(9),50,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2825 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(9),50,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1190 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3419 No. of Facilities: 64 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 1967 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3419 No. of Facilities: 787 (estimated) No. of Industries: 13 No. of Occupations: 12 No. of Employees: 5579 (estimated) No. of Female Employees: 861 (estimated)

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H312-H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R21;R34
Safety Phrases S26-S36/37/39-S45-S24/25
RIDADR UN 3055 8/PG 3
WGK Germany 1
RTECS KJ6125000
Packaging Group III
Hazard Class 8
HS Code 29221980

 Synthetic Route

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles4

More Articles
The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension.

PLoS ONE 10 , e0136780, (2015)

The surface of aligned, electrospun poly-L-lactic acid (PLLA) fibers was chemically modified to determine if surface chemistry and hydrophilicity could improve neurite extension from chick dorsal root...

Synthesis and biological evaluation of ureido and thioureido derivatives of 2-amino-2-deoxy-D-glucose and related aminoalcohols as N-acetyl-beta-D-hexosaminidase inhibitors.

Carbohydr. Res. 314(1-2) , 47-63, (1998)

Ureido and thioureido derivatives of 2-acetamido-2-deoxy-beta-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-beta-D-hexosaminidase (NAHase) inhibitors and...

Design of quantum dot-conjugated lipids for long-term, high-speed tracking experiments on cell surfaces.

J. Am. Chem. Soc. 130(45) , 15054-62, (2008)

The current study reports the facile design of quantum dot (QD)-conjugated lipids and their application to high-speed tracking experiments on cell surfaces. CdSe/ZnS core/shell QDs with two types of h...

 Synonyms

Diethylene glycol amine
2,6-DIMETHYLTHIOPHENOL
MFCD00008181
5-Hydroxy-3-oxapentylamine
2-(2-hydroxyethoxy)ethanamine
β-(β-Hydroxyethoxy)ethylamine
diethylene glycol monoamine
Ethanol, 2- (2-aminoethoxy)-
β-Hydroxy-β'-aminodiethyl ether
Ethanol,2-(2-aminoethoxy)
3,6-dioxa-1-hexylamine
UNII-6R5Y84T8W9
2-(2-amino-ethoxy)-ethanol
5-Aminoethyl 2-hydroxyethyl ether
Diglycolamine
EINECS 213-195-4
N-2-hydroxyethoxyethylamine
1-amino-3-oxapentane-5-ol
2-Amino-2'-hydroxydiethyl ether
2-(2-Aminoethoxy)ethanol
Ethanol, 2-(2-aminoethoxy)-
2-(2-hydroxyethoxy)ethylamine
2-Aminoethoxyethanol
1-Amino-2-(2-hydroxyethoxy)ethane
β-Hydroxy-β'-aminoethyl ether
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