4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl

Modify Date: 2025-08-22 11:32:01

4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl Structure
4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl structure
Common Name 4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl
CAS Number 6307-35-3 Molecular Weight 204.02500
Density 2.04 g/cm3 Boiling Point 280.9ºC at 760 mmHg
Molecular Formula C5H6BrN3O Melting Point 244-246 °C(lit.)
MSDS Chinese USA Flash Point 123.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.04 g/cm3
Boiling Point 280.9ºC at 760 mmHg
Melting Point 244-246 °C(lit.)
Molecular Formula C5H6BrN3O
Molecular Weight 204.02500
Flash Point 123.7ºC
Exact Mass 202.96900
PSA 72.03000
LogP 1.41650
Index of Refraction 1.719

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933599090

 Synthetic Route

~%

4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl Structure

4(3H)-Pyrimidin...

CAS#:6307-35-3

Literature: Journal of the Chemical Society, , p. 41,45 Journal of the American Chemical Society, , vol. 68, p. 766,768

~21%

4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl Structure

4(3H)-Pyrimidin...

CAS#:6307-35-3

Literature: Watanabe, K. A.; Su, T.-L.; Pankiewicz, K. W.; Harada, K. Heterocycles, 1984 , vol. 21, # 1 p. 289 - 307

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles7

More Articles
Comparation interferon- inducing and antiviral properties of 2-amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), tilorone hydrochloride, and polyinosinic-polycytidylic acid.

Antimicrob. Agents Chemother. 11(6) , 984-92, (1977)

2-Amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), polyinosinic acid-polycytidylic acid [poly(I:C)], and tilorone HCl induced high levels of serum interferon in mice. Each consequently protected mice ...

Enhancement of resistance to Listeria monocytogenes infection in mice by pyrimidine analogs.

Clin. Invest. Med. 7(4) , 343-8, (1984)

The modulation of murine host resistance to infection with Listeria monocytogenes by the substituted pyrimidine anti-viral compounds, 2-amino-5-bromo-6-methyl-4-pyrimidinol (ABMP), 2-amino-5-bromo-6-p...

Antineoplastic properties of pyrimidinone interferon inducers.

Adv. Enzyme Regul. 19 , 335-48, (1980)

 Bioassay

View more

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Protective index was measured on herpes simplex virus type 1(HSV-1) infected mice at ...
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL692869
Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Tested for in vivo antiviral activity against semliki forest virus in mice after intr...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL720732
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
Name: Serum interferon response from a single ip administration of 800 mg/kg employing a pl...
Source: ChEMBL
Target: L929
External Id: CHEMBL711873
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600
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 Synonyms

2-amino-5-bromo-6-methylpyrimidin-4(1H)-one
2-Amino-5-bromo-4-hydroxy-6-methylpyrimidine
2-amino-5-bromo-6-methyl-3H-pyrimidin-4-one
2-Amino-5-bromo-6-methyl-4-pyrimidinol
ABMP
MFCD00006092
2-amino-5-bromo-6-methylpyrimid-4-one
EINECS 228-623-5
2-amino-5-bromo-6-methylpyrimidin-4-ol
2-amino-5-bromo-4-hydroxyl-6-methylpyrimidine
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