4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl
4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl structure
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Common Name | 4(3H)-Pyrimidinone,2-amino-5-bromo-6-methyl | ||
|---|---|---|---|---|
| CAS Number | 6307-35-3 | Molecular Weight | 204.02500 | |
| Density | 2.04 g/cm3 | Boiling Point | 280.9ºC at 760 mmHg | |
| Molecular Formula | C5H6BrN3O | Melting Point | 244-246 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 123.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 2.04 g/cm3 |
|---|---|
| Boiling Point | 280.9ºC at 760 mmHg |
| Melting Point | 244-246 °C(lit.) |
| Molecular Formula | C5H6BrN3O |
| Molecular Weight | 204.02500 |
| Flash Point | 123.7ºC |
| Exact Mass | 202.96900 |
| PSA | 72.03000 |
| LogP | 1.41650 |
| Index of Refraction | 1.719 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933599090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~%
4(3H)-Pyrimidin... CAS#:6307-35-3 |
| Literature: Journal of the Chemical Society, , p. 41,45 Journal of the American Chemical Society, , vol. 68, p. 766,768 |
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~21%
4(3H)-Pyrimidin... CAS#:6307-35-3 |
| Literature: Watanabe, K. A.; Su, T.-L.; Pankiewicz, K. W.; Harada, K. Heterocycles, 1984 , vol. 21, # 1 p. 289 - 307 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 2 | |
![6-bromo-2-(4-methoxyphenyl)-7-methyl-8H-imidazo[1,2-a]pyrimidin-5-one structure](https://image.chemsrc.com/caspic/283/14247-78-0.png)
CAS#:14247-78-0
CAS#:6314-12-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Comparation interferon- inducing and antiviral properties of 2-amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), tilorone hydrochloride, and polyinosinic-polycytidylic acid.
Antimicrob. Agents Chemother. 11(6) , 984-92, (1977) 2-Amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), polyinosinic acid-polycytidylic acid [poly(I:C)], and tilorone HCl induced high levels of serum interferon in mice. Each consequently protected mice ... |
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Enhancement of resistance to Listeria monocytogenes infection in mice by pyrimidine analogs.
Clin. Invest. Med. 7(4) , 343-8, (1984) The modulation of murine host resistance to infection with Listeria monocytogenes by the substituted pyrimidine anti-viral compounds, 2-amino-5-bromo-6-methyl-4-pyrimidinol (ABMP), 2-amino-5-bromo-6-p... |
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Antineoplastic properties of pyrimidinone interferon inducers.
Adv. Enzyme Regul. 19 , 335-48, (1980)
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This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
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Name: Protective index was measured on herpes simplex virus type 1(HSV-1) infected mice at ...
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL692869
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Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: Tested for in vivo antiviral activity against semliki forest virus in mice after intr...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL720732
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Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
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Name: Serum interferon response from a single ip administration of 800 mg/kg employing a pl...
Source: ChEMBL
Target: L929
External Id: CHEMBL711873
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Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
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Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-amino-5-bromo-6-methylpyrimidin-4(1H)-one |
| 2-Amino-5-bromo-4-hydroxy-6-methylpyrimidine |
| 2-amino-5-bromo-6-methyl-3H-pyrimidin-4-one |
| 2-Amino-5-bromo-6-methyl-4-pyrimidinol |
| ABMP |
| MFCD00006092 |
| 2-amino-5-bromo-6-methylpyrimid-4-one |
| EINECS 228-623-5 |
| 2-amino-5-bromo-6-methylpyrimidin-4-ol |
| 2-amino-5-bromo-4-hydroxyl-6-methylpyrimidine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: The English name of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one. |
| Q: What is the safety information for 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: Safety information for 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one: S26-S36. |
| Q: What is the LogP of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: LogP of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is 1.41650. |
| Q: What is the boiling point of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: Boiling point of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is 280.9ºC at 760 mmHg. |
| Q: What is the molecular weight of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: Molecular weight of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is 204.02500. |
| Q: What are the downstream products of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: Related downstream products(CAS) of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one: 14247-78-0;6314-12-1. |
| Q: What is the CAS number of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: CAS number of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is 6307-35-3. |
| Q: What English synonyms does 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one have? |
| A: English synonyms of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one: 2-amino-5-bromo-6-methylpyrimidin-4(1H)-one, 2-Amino-5-bromo-4-hydroxy-6-methylpyrimidine, 2-amino-5-bromo-6-methyl-3H-pyrimidin-4-one, 2-Amino-5-bromo-6-methyl-4-pyrimidinol, ABMP, MFCD00006092, 2-amino-5-bromo-6-methylpyrimid-4-one, EINECS 228-623-5, 2-amino-5-bromo-6-methylpyrimidin-4-ol, 2-amino-5-bromo-4-hydroxyl-6-methylpyrimidine. |
| Q: What is the polar surface area (PSA) of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: Polar surface area (PSA) of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is 72.03000. |
| Q: What is the molecular formula of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one? |
| A: Molecular formula of 2-amino-5-bromo-6-methyl-1H-pyrimidin-4-one is C5H6BrN3O. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |