2-Amino-6-hydroxy-4-methylpyrimidine

Modify Date: 2025-08-24 11:14:55

2-Amino-6-hydroxy-4-methylpyrimidine Structure
2-Amino-6-hydroxy-4-methylpyrimidine structure
Common Name 2-Amino-6-hydroxy-4-methylpyrimidine
CAS Number 3977-29-5 Molecular Weight 125.129
Density 1.3±0.1 g/cm3 Boiling Point 385.9±34.0 °C at 760 mmHg
Molecular Formula C5H7N3O Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 187.2±25.7 °C

 Names

Name 2-Amino-4-hydroxy-6-methylpyrimidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 385.9±34.0 °C at 760 mmHg
Melting Point >300 °C(lit.)
Molecular Formula C5H7N3O
Molecular Weight 125.129
Flash Point 187.2±25.7 °C
Exact Mass 125.058914
PSA 72.03000
LogP -0.55
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.638
InChIKey KWXIPEYKZKIAKR-UHFFFAOYSA-N
SMILES Cc1cc(=O)[nH]c(N)n1

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S24/25-S36/37/39-S26-S22
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UW7362250
HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways.

PLoS Pathog. 6 , e1000865, (2010)

Riboswitches are regulatory elements modulating gene expression in response to specific metabolite binding. It has been recently reported that riboswitch agonists may exhibit antimicrobial properties ...

 2-Amino-6-hydroxy-4-methylpyrimidineBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Identifying Sarm1 TIR NADase inhibitors through high throughput HPLC assay
Source: 24386
Target: N/A
External Id: Sarm1 TIR NADase inhibitors
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 Synonyms

2-Amino-6-methylpyrimidin-4(1H)-one
2-Amino-6-hydroxy-4-methylpyrimidine
2-amino-6-methyl-1H-pyrimidin-4-one
EINECS 223-612-1
2-Amino-6-methyl-4-pyrimidinol
MFCD00006095
2-amino-6-methylpyrimidin-4-ol
2-amino-4-methyl-6-hydroxypyrimidine
2-Amino-6-methylpyrimidin-4(3H)-one
2-Amino-6-methyl-4(1H)-pyrimidinone
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