2-Hydroxy-1,4-naphoquinone

Modify Date: 2026-07-12 20:37:49

2-Hydroxy-1,4-naphoquinone structure	Common Name	2-Hydroxy-1,4-naphoquinone
	CAS Number	83-72-7	Molecular Weight	174.153
	Density	1.5±0.1 g/cm3	Boiling Point	339.9±42.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₆O₃	Melting Point	192-195 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	173.6±24.4 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2-Hydroxy-1,4-naphoquinone

Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity[1].

Summary: 2-羟基-1,4-萘醌 (lawsone), also known as 2-Hydroxy-1,4-naphoquinone, has a CAS number of 83-72-7 and a molecular formula of C10H6O3, with a molecular weight of 174.153. It appears as white cubic crystals, with a melting point of 192-195 °C and a boiling point of 339.9±42.0 °C, and a density of 1.5±0.1 g/cm³. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	lawsone
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Tripathi RD, et al. A fungitoxic principle from the leaves of lawsonia inermis lam. Experientia. 1978 Jan 15;34(1):51-2.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.5±0.1 g/cm3
Boiling Point	339.9±42.0 °C at 760 mmHg
Melting Point	192-195 °C (dec.)(lit.)
Molecular Formula	C₁₀H₆O₃
Molecular Weight	174.153
Flash Point	173.6±24.4 °C
Exact Mass	174.031693
PSA	54.37000
LogP	1.55
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.681
InChIKey	WVCHIGAIXREVNS-UHFFFAOYSA-N
SMILES	O=C1C=C(O)c2ccccc2C1=O
Water Solubility	2 g/L (20 ºC)

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

2-Hydroxy-1,4-naphoquinone MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL8200000

CHEMICAL NAME :: 1,4-Naphthoquinone, 2-hydroxy-

CAS REGISTRY NUMBER :: 83-72-7

BEILSTEIN REFERENCE NO. :: 1565260

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H6-O3

MOLECULAR WEIGHT :: 174.16

WISWESSER LINE NOTATION :: L66 BV EVJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 522 mg/kg/6D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in spleen Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,61,1995 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9568 No. of Facilities: 227 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 2271 (estimated) No. of Female Employees: 1817 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36;R68
Safety Phrases	S26-S37/39-S36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	QL8200000
Packaging Group	II
HS Code	2914690090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 9
CAS#:132-86-5 Naphthoresorcinol CAS#:35135-38-7 2-Hydroxy-3-iod... CAS#:574-00-5 benzocatechol CAS#:1785-67-7 1,2,4-Naphthale...
CAS#:13302-67-5 naphthalene-1,2... CAS#:93-04-9 2-Methoxynaphthalene CAS#:571-60-8 BENZOHYDROQUINONE CAS#:1526-73-4 1,4-Naphthalene...
CAS#:130-15-4 1,4-naphthoquinone
DownStream 10
CAS#:105438-31-1 3-(2-ethylbut-1... CAS#:106932-37-0 3-hept-1-enyl-4... CAS#:606-23-5 1,3-INDANDIONE CAS#:33440-64-1 bi-lawsone
CAS#:35135-38-7 2-Hydroxy-3-iod... CAS#:433-06-7 2,2,2-trifluoro... CAS#:4707-32-8 Beta-Lapachone CAS#:4707-33-9 alpha-Lapachone
CAS#:92458-44-1 Deschloro Atovaquone CAS#:18093-50-0 1,4-Naphthalene...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Sensitive electrochemical detection of Salmonella with chitosan-gold nanoparticles composite film.

Talanta 140 , 122-7, (2015)

An ultrasensitive electrochemical immunosensor for detection of Salmonella has been developed based on using high density gold nanoparticles (GNPs) well dispersed in chitosan hydrogel and modified gla...

Allergic contact dermatitis caused by mehindi: a further case.

G. Ital. Dermatol. Venereol. 148(2) , 234-5, (2013)

Irritant contact dermatitis from a black henna tattoo without sensitization to para-phenylendiamine.

Pediatrics 131(6) , e1974-6, (2013)

Allergic contact dermatitis from nonpermanent black henna tattoos has been frequently reported, particularly in children. Contamination or adulteration of the dyes with para-phenylendiamine has been i...

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

C.I. Natural Orange 6

MFCD00001678

2-Hydroxy-1,4-naphthochinone

2-Hydroxy-1,4-naphoquinone

EINECS 201-496-3

2-Hydroxy-1,4-naphthoquinone

hydroxynaphthoquinone

Natural Orange 6

2-Hydroxy-p-naphthoquinone

2-hydroxynaphthalene-1,4-dione

hennotannic acid

lawsone

2-Hydroxy-1,4-napthoquinone

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: How is the water solubility of lawsone?

A: Water solubility of lawsone: 2 g/L (20 ºC).

Q: What is the molecular weight of lawsone?

A: Molecular weight of lawsone is 174.153.

Q: What is the boiling point of lawsone?

A: Boiling point of lawsone is 339.9±42.0 °C at 760 mmHg.

Q: What are the uses of lawsone?

A: Main uses of lawsone: Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity[1].

Q: What is the InChIKey of lawsone?

A: InChIKey of lawsone is WVCHIGAIXREVNS-UHFFFAOYSA-N.

Q: What is the SMILES notation of lawsone?

A: SMILES notation of lawsone is O=C1C=C(O)c2ccccc2C1=O.

Q: What are the upstream materials of lawsone?

A: Related upstream materials(CAS) of lawsone: 132-86-5;35135-38-7;574-00-5;1785-67-7;13302-67-5;93-04-9;571-60-8;1526-73-4;130-15-4.

Q: What English synonyms does lawsone have?

A: English synonyms of lawsone: C.I. Natural Orange 6, MFCD00001678, 2-Hydroxy-1,4-naphthochinone, 2-Hydroxy-1,4-naphoquinone, EINECS 201-496-3, 2-Hydroxy-1,4-naphthoquinone, hydroxynaphthoquinone, Natural Orange 6, 2-Hydroxy-p-naphthoquinone, 2-hydroxynaphthalene-1,4-dione, hennotannic acid, lawsone, 2-Hydroxy-1,4-napthoquinone.

Q: What is the safety information for lawsone?

A: Safety information for lawsone: S26-S37/39-S36/37/39.

Q: What is the polar surface area (PSA) of lawsone?

A: Polar surface area (PSA) of lawsone is 54.37000.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Henan Tianfu Chemical Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Hydroxy-1,4-naphoquinone
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 83-72-7 2-Hydroxy-1,4-naphoquinone
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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