4-Fluoro-3-methoxyaniline

Modify Date: 2026-08-02 18:56:11

4-Fluoro-3-methoxyaniline Structure
4-Fluoro-3-methoxyaniline structure
Common Name 4-Fluoro-3-methoxyaniline
CAS Number 64465-53-8 Molecular Weight 141.143
Density 1.2±0.1 g/cm3 Boiling Point 252.5±20.0 °C at 760 mmHg
Molecular Formula C7H8FNO Melting Point 66-68ºC
MSDS USA Flash Point 106.5±21.8 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 4-Fluoro-3-methoxyaniline
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.2±0.1 g/cm3
Boiling Point 252.5±20.0 °C at 760 mmHg
Melting Point 66-68ºC
Molecular Formula C7H8FNO
Molecular Weight 141.143
Flash Point 106.5±21.8 °C
Exact Mass 141.058990
PSA 35.25000
LogP 1.00
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.532
InChIKey XAACOEWSHBIFGJ-UHFFFAOYSA-N
SMILES COc1cc(N)ccc1F

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 4-Fluoro-3-methoxyaniline
Synonyms:5-Amino-2-fluoroanisole

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
H315:Causes skin irritation
H318:Causes serious eye damage
H335:May cause respiratory irritation
Harmful to aquatic life with long lasting effects
H412:
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P273:Avoid release to the environment
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:4-Fluoro-3-methoxyaniline
CAS number:64465-53-8

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C7H8FNO
Molecular weight:141.1

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi
Risk Phrases R20/21/22
Safety Phrases 26-36/37/39
HS Code 2922299090

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-fluoro-3-methoxy-aniline
5-Amino-2-fluoroanisole
MFCD00665789
4-fluoro-3-methoxy-phenylamine
3-methoxy-4-fluoroaniline
4-Fluoro-3-methoxy-anilin
4-Fluoro-3-methoxyaniline
4-fluoro-3-methoxybenzenamine

 4-Fluoro-3-methoxyaniline | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular formula of 4-Fluoro-3-methoxyaniline?
A: Molecular formula of 4-Fluoro-3-methoxyaniline is C7H8FNO.
Q: What is the InChIKey of 4-Fluoro-3-methoxyaniline?
A: InChIKey of 4-Fluoro-3-methoxyaniline is XAACOEWSHBIFGJ-UHFFFAOYSA-N.
Q: What is the polar surface area (PSA) of 4-Fluoro-3-methoxyaniline?
A: Polar surface area (PSA) of 4-Fluoro-3-methoxyaniline is 35.25000.
Q: What is the safety information for 4-Fluoro-3-methoxyaniline?
A: Safety information for 4-Fluoro-3-methoxyaniline: 26-36/37/39.
Q: What is the melting point of 4-Fluoro-3-methoxyaniline?
A: Melting point of 4-Fluoro-3-methoxyaniline is 66-68ºC.
Q: What is the molecular weight of 4-Fluoro-3-methoxyaniline?
A: Molecular weight of 4-Fluoro-3-methoxyaniline is 141.143.
Q: What is the CAS number of 4-Fluoro-3-methoxyaniline?
A: CAS number of 4-Fluoro-3-methoxyaniline is 64465-53-8.
Q: What English synonyms does 4-Fluoro-3-methoxyaniline have?
A: English synonyms of 4-Fluoro-3-methoxyaniline: 4-fluoro-3-methoxy-aniline, 5-Amino-2-fluoroanisole, MFCD00665789, 4-fluoro-3-methoxy-phenylamine, 3-methoxy-4-fluoroaniline, 4-Fluoro-3-methoxy-anilin, 4-Fluoro-3-methoxyaniline, 4-fluoro-3-methoxybenzenamine.
Q: What is the SMILES notation of 4-Fluoro-3-methoxyaniline?
A: SMILES notation of 4-Fluoro-3-methoxyaniline is COc1cc(N)ccc1F.
Q: What is the boiling point of 4-Fluoro-3-methoxyaniline?
A: Boiling point of 4-Fluoro-3-methoxyaniline is 252.5±20.0 °C at 760 mmHg.

 4-Fluoro-3-methoxyanilinefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
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