H1-7 acetate salt

Modify Date: 2024-01-14 07:57:32

H1-7 acetate salt Structure
H1-7 acetate salt structure
Common Name H1-7 acetate salt
CAS Number 65189-70-0 Molecular Weight 770.88100
Density 1.54g/cm3 Boiling Point N/A
Molecular Formula C31H58N14O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H1-7 acetate salt


H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate[1][2].

 Names

Name 1-[2-[[2-[2-[[6-amino-2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]propanoylamino]-3-hydroxypropanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid
Synonym More Synonyms

 H1-7 acetate salt Biological Activity

Description H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate[1][2].
Related Catalog
In Vitro H1-7 (histone H1 phosphorylation site), PKA Substrate可用于检测 PKA 活性[2]。
References

[1]. Pomerantz AH, et, al. Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4261-5.  

[2]. Arif A, et, al. EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. Nature. 2017 Feb 16;542(7641):357-361.  

 Chemical & Physical Properties

Density 1.54g/cm3
Molecular Formula C31H58N14O9
Molecular Weight 770.88100
Exact Mass 770.45100
PSA 399.18000
Index of Refraction 1.671

 Synonyms

HISTONE H1 PHOSPHORYLATION SITE
Histone-7
Cyclic-AMP dependent protein kinase substrate
ARG-ARG-LYS-ALA-SER-GLY-PRO
1-{2-[2-(2-{6-amino-2-[2-(2-amino-5-carbamimidamidopentanamido)-5-carbamimidamidopentanamido]hexanamido}propanamido)-3-hydroxypropanamido]acetyl}pyrrolidine-2-carboxylic acid
H1-7 (histone H1 phosphorylation site),PKA Substrate
Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH
ARG-ARG-LYS-ALA-SER-GLY-PRO: RRKASGP
RRKASGP
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