3-(2,4-Dihydroxybenzylidene)-5-(4-methoxyphenyl)-2(3H)-furanone
Modify Date: 2025-09-12 20:46:49
3-(2,4-Dihydroxybenzylidene)-5-(4-methoxyphenyl)-2(3H)-furanone structure
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Common Name | 3-(2,4-Dihydroxybenzylidene)-5-(4-methoxyphenyl)-2(3H)-furanone | ||
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| CAS Number | 6621-92-7 | Molecular Weight | 310.30100 | |
| Density | 1.408g/cm3 | Boiling Point | 617.2ºC at 760 mmHg | |
| Molecular Formula | C18H14O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 231.7ºC | |
Use of 3-(2,4-Dihydroxybenzylidene)-5-(4-methoxyphenyl)-2(3H)-furanoneALR-6 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-6 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM and has no significant effect on direct inhibition of 5-LOX[1]. |
| Name | 3-[(2,4-dihydroxyphenyl)methylidene]-5-(4-methoxyphenyl)furan-2-one |
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| Description | ALR-6 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-6 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM and has no significant effect on direct inhibition of 5-LOX[1]. |
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| Related Catalog | |
| Target |
FLAP[1] |
| References |
| Density | 1.408g/cm3 |
|---|---|
| Boiling Point | 617.2ºC at 760 mmHg |
| Molecular Formula | C18H14O5 |
| Molecular Weight | 310.30100 |
| Flash Point | 231.7ºC |
| Exact Mass | 310.08400 |
| PSA | 75.99000 |
| LogP | 3.08770 |
| Index of Refraction | 1.701 |
| InChIKey | ZOHPXEDJWXZOLY-JYRVWZFOSA-N |
| SMILES | COc1ccc(C2=CC(=Cc3ccc(O)cc3O)C(=O)O2)cc1 |