BEAUCAGE REAGENT

Modify Date: 2025-08-27 18:35:41

BEAUCAGE REAGENT Structure
BEAUCAGE REAGENT structure
Common Name BEAUCAGE REAGENT
CAS Number 66304-01-6 Molecular Weight 200.235
Density 1.7±0.1 g/cm3 Boiling Point 414.6±28.0 °C at 760 mmHg
Molecular Formula C7H4O3S2 Melting Point 103-107 °C(lit.)
MSDS N/A Flash Point 204.6±24.0 °C

 Use of BEAUCAGE REAGENT


Beaucage reagent is found to be potent in causing DNA cleavage.

 Names

Name 3H-1,2-Benzodithiol-3-one 1,1-dioxide
Synonym More Synonyms

 BEAUCAGE REAGENT Biological Activity

Description Beaucage reagent is found to be potent in causing DNA cleavage.
Related Catalog
References

[1]. Zheng J, et al. Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent. Org Biomol Chem. 2010 Mar 21;8(6):1293-5.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 414.6±28.0 °C at 760 mmHg
Melting Point 103-107 °C(lit.)
Molecular Formula C7H4O3S2
Molecular Weight 200.235
Flash Point 204.6±24.0 °C
Exact Mass 199.960190
PSA 84.89000
LogP 1.13
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.690
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S37/39-S26
RIDADR 3335
WGK Germany 3
HS Code 2930909090

 Synthetic Route

~47%

BEAUCAGE REAGENT Structure

BEAUCAGE REAGENT

CAS#:66304-01-6

Literature: Regan, J. B.; Phillips, L. R.; Beaucage, S. L. Organic Preparations and Procedures International, 1992 , vol. 24, # 4 p. 488 - 492

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BEAUCAGE REAGENT Structure

BEAUCAGE REAGENT

CAS#:66304-01-6

Literature: Synthesis, , # 1 p. 43 - 45

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

3H-1,2-Benzodithiol-3-one, 1,1-dioxide
1,1-dioxo-1λ<sup>6</sup>,2-benzodithiol-3-one
3H-1,2-Benzodithiol-3-one 1,1-dioxide
MFCD00132960
BEAUCAGE REAGENT
1,2-benzodithiol-3-one-1,1-dioxide
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