ANSAMITOCIN P-4

Modify Date: 2024-01-17 18:32:47

ANSAMITOCIN P-4 Structure
ANSAMITOCIN P-4 structure
 Common Name ANSAMITOCIN P-4
CAS Number 66547-10-2 Molecular Weight 649.17100
Density 1.28g/cm3 Boiling Point 838.7ºC at 760 mmHg
Molecular Formula C33H45ClN2O9 Melting Point N/A
MSDS N/A Flash Point 461ºC

 Names

Name Maytansine, 3-de(2-(acetylmethylamino)-1-oxopropoxy)-3-(3-methyl-1-oxobutoxy)
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 838.7ºC at 760 mmHg
Molecular Formula C33H45ClN2O9
Molecular Weight 649.17100
Flash Point 461ºC
Exact Mass 648.28100
PSA 136.16000
LogP 5.10750
Index of Refraction 1.58

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OQ2295000
CHEMICAL NAME :
Maytansine, 3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-, isovalerate (ester)
CAS REGISTRY NUMBER :
66547-10-2
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C33-H45-Cl-N2-O9
MOLECULAR WEIGHT :
649.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
625 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - mouse Ascites tumor
DOSE/DURATION :
4 ug/kg
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1707,1980

 Synonyms

Tam 340
ansamitocin P-4
Maytansinol isovalerate
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