Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ANSAMITOCIN P-4
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66547-10-2

66547-10-2 structure

66547-10-2 structure

Name: ANSAMITOCIN P-4
Chemical Name: Maytansine, 3-de(2-(acetylmethylamino)-1-oxopropoxy)-3-(3-methyl-1-oxobutoxy)
CAS Number: 66547-10-2
Molecular Formula: C₃₃H₄₅ClN₂O₉
Molecular Weight: 649.17100
Create Date: 2017-05-11 05:20:08
Modify Date: 2024-01-17 18:32:47

Name	Maytansine, 3-de(2-(acetylmethylamino)-1-oxopropoxy)-3-(3-methyl-1-oxobutoxy)
Synonyms	Tam 340 ansamitocin P-4 Maytansinol isovalerate

Density	1.28g/cm3
Boiling Point	838.7ºC at 760 mmHg
Molecular Formula	C₃₃H₄₅ClN₂O₉
Molecular Weight	649.17100
Flash Point	461ºC
Exact Mass	648.28100
PSA	136.16000
LogP	5.10750
Index of Refraction	1.58

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OQ2295000

CHEMICAL NAME :: Maytansine, 3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-, isovalerate (ester)

CAS REGISTRY NUMBER :: 66547-10-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C33-H45-Cl-N2-O9

MOLECULAR WEIGHT :: 649.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 4 ug/kg

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1707,1980