N-trans-Feruloyltyramine

Modify Date: 2024-01-07 10:52:15

N-trans-Feruloyltyramine Structure
N-trans-Feruloyltyramine structure
 Common Name N-trans-Feruloyltyramine
CAS Number 66648-43-9 Molecular Weight 313.348
Density 1.2±0.1 g/cm3 Boiling Point 554.2±60.0 °C at 760 mmHg
Molecular Formula C18H19NO4 Melting Point N/A
MSDS Chinese USA Flash Point 289.0±32.9 °C
Symbol GHS09
GHS09		 Signal Word Warning

 Use of N-trans-Feruloyltyramine


N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid from Piper nigru, is an inhibitor of COX1 and COX2, with potential antioxidant properties. N-trans-Feruloyltyramine possesses anti-inflammatory activity[1].

 Names

Name (2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]ac rylamide
Synonym More Synonyms

 N-trans-Feruloyltyramine Biological Activity

Description N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid from Piper nigru, is an inhibitor of COX1 and COX2, with potential antioxidant properties. N-trans-Feruloyltyramine possesses anti-inflammatory activity[1].
Related Catalog
Target

COX-1

COX-2

References

[1]. Aswad M, et al. Nature is the best source of anti-inflammatory drugs: indexing natural products for their anti-inflammatory bioactivity. Inflamm Res. 2018 Jan;67(1):67-75.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 554.2±60.0 °C at 760 mmHg
Molecular Formula C18H19NO4
Molecular Weight 313.348
Flash Point 289.0±32.9 °C
Exact Mass 313.131409
PSA 78.79000
LogP 3.33
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.566
Storage condition ?20°C

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H410
Precautionary Statements P273-P501
Hazard Codes N
Risk Phrases 50
Safety Phrases 61
RIDADR UN 3077 9 / PGIII

 Precursor & DownStream

Precursor  0

DownStream  2

 Articles26

More Articles
Transgenic tomato plants overexpressing tyramine N-hydroxycinnamoyltransferase exhibit elevated hydroxycinnamic acid amide levels and enhanced resistance to Pseudomonas syringae.

Mol. Plant Microbe Interact. 27(10) , 1159-69, (2014)

Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, an...

A feruloyltyramine trimer isolated from potato common scab lesions

Phytochemistry 71(17-18) , 2187-9, (2010)

Graphical abstract A lignanamide isolated from potato common scab lesions was characterized as a feruloyltyramine trimer by MS and NMR techniques.

Endosperm-specific expression of serotonin N-hydroxycinnamoyltransferase in rice.

Plant Foods Hum. Nutr. 63(2) , 53-7, (2008)

Serotonin N-hydroxycinnamoyltransferase (SHT) is a key enzyme in the synthesis of feruloylserotonin (FS) and 4-coumaroylserotonin (CS). These serotonin derivatives show strong antioxidant activity, ma...

 Synonyms

6,7-dimethoxy-5-hydroxyflavone
5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one
N-trans-Feruloyltyramine
(1E,2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-propenimidic acid
5-Hydroxy-6,7-dimethoxyflavone
(2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide
5-hydroxy-6,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one
6,7-di-O-methyl-baicalein
moupinamide
2-Propenimidic acid, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (1E,2E)-
4H-1-Benzopyran-4-one,5-hydroxy-6,7-dimethoxy-2-phenyl
baicalein 6,7-dimethyl ether
2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (2E)-
Mosloflavone
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