6-Monohydroxyflavone
6-Monohydroxyflavone structure
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Common Name | 6-Monohydroxyflavone | ||
|---|---|---|---|---|
| CAS Number | 6665-83-4 | Molecular Weight | 238.238 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 450.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C15H10O3 | Melting Point | 234-236 °C(lit.) | |
| MSDS | N/A | Flash Point | 176.3±22.2 °C | |
Use of 6-Monohydroxyflavone6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 6-Hydroxyflavone |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 450.1±45.0 °C at 760 mmHg |
| Melting Point | 234-236 °C(lit.) |
| Molecular Formula | C15H10O3 |
| Molecular Weight | 238.238 |
| Flash Point | 176.3±22.2 °C |
| Exact Mass | 238.062988 |
| PSA | 50.44000 |
| LogP | 3.72 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.666 |
| InChIKey | GPZYYYGYCRFPBU-UHFFFAOYSA-N |
| SMILES | O=c1cc(-c2ccccc2)oc2ccc(O)cc12 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| WGK Germany | 3 |
| HS Code | 2914400090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2914400090 |
|---|---|
| Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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|
Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936125
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Name: Antioxidant activity assessed as ferric ion reducing activity using fe3+-TPTZ at 1 mM...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1936124
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|
Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
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|
Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936127
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|
Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936126
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|
Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936128
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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|
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| EINECS 229-704-8 |
| 6-Monohydroxyflavone |
| MFCD00017329 |
| 6-hydroxy-2-phenylchromen-4-one |
| 6-Hydroxy-2-phenyl-4H-chromen-4-one |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 6-Hydroxyflavone? |
| A: Molecular weight of 6-Hydroxyflavone is 238.238. |
| Q: What is the safety information for 6-Hydroxyflavone? |
| A: Safety information for 6-Hydroxyflavone: S26-S37/39. |
| Q: What is the polar surface area (PSA) of 6-Hydroxyflavone? |
| A: Polar surface area (PSA) of 6-Hydroxyflavone is 50.44000. |
| Q: What is the boiling point of 6-Hydroxyflavone? |
| A: Boiling point of 6-Hydroxyflavone is 450.1±45.0 °C at 760 mmHg. |
| Q: What is the melting point of 6-Hydroxyflavone? |
| A: Melting point of 6-Hydroxyflavone is 234-236 °C(lit.). |
| Q: What is the CAS number of 6-Hydroxyflavone? |
| A: CAS number of 6-Hydroxyflavone is 6665-83-4. |
| Q: What is the SMILES notation of 6-Hydroxyflavone? |
| A: SMILES notation of 6-Hydroxyflavone is O=c1cc(-c2ccccc2)oc2ccc(O)cc12. |
| Q: What is the LogP of 6-Hydroxyflavone? |
| A: LogP of 6-Hydroxyflavone is 3.72. |
| Q: What is the molecular formula of 6-Hydroxyflavone? |
| A: Molecular formula of 6-Hydroxyflavone is C15H10O3. |
| Q: What is the English name of 6-Hydroxyflavone? |
| A: The English name of 6-Hydroxyflavone is 6-Hydroxyflavone. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |