6-Monohydroxyflavone

Modify Date: 2025-08-23 12:52:36

6-Monohydroxyflavone structure	Common Name	6-Monohydroxyflavone
	CAS Number	6665-83-4	Molecular Weight	238.238
	Density	1.3±0.1 g/cm3	Boiling Point	450.1±45.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₁₀O₃	Melting Point	234-236 °C(lit.)
	MSDS	N/A	Flash Point	176.3±22.2 °C

Use of 6-Monohydroxyflavone

6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].

Name	6-Hydroxyflavone
Synonym	More Synonyms

Description	6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52. [2]. Lai CH, et al. Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells. Evid Based Complement Alternat Med. 2014;2014:924560. [3]. Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52.

[2]. Lai CH, et al. Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells. Evid Based Complement Alternat Med. 2014;2014:924560.

[3]. Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409.

Density	1.3±0.1 g/cm3
Boiling Point	450.1±45.0 °C at 760 mmHg
Melting Point	234-236 °C(lit.)
Molecular Formula	C₁₅H₁₀O₃
Molecular Weight	238.238
Flash Point	176.3±22.2 °C
Exact Mass	238.062988
PSA	50.44000
LogP	3.72
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.666
InChIKey	GPZYYYGYCRFPBU-UHFFFAOYSA-N
SMILES	O=c1cc(-c2ccccc2)oc2ccc(O)cc12

6-Monohydroxyflavone MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
WGK Germany	3
HS Code	2914400090

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936125

Name: Antioxidant activity assessed as ferric ion reducing activity using fe3+-TPTZ at 1 mM...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1936124

Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186

Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936127

Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936126

Name: Antioxidant activity against toxin solution-induced lipid peroxidation in Sprague-Daw...
Source: ChEMBL
Target: Brain
External Id: CHEMBL1936128

Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN

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EINECS 229-704-8

6-Monohydroxyflavone

MFCD00017329

6-hydroxy-2-phenylchromen-4-one

6-Hydroxy-2-phenyl-4H-chromen-4-one

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China
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naturewill
China
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Purity: 98.0%
Delivery: Inquiry
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 6-Monohydroxyflavone
Price: ￥658.0/100mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

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Price: ￥550/10 mM * 1 mL in DMSO

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6-Monohydroxyflavone

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.