Ethyl pyruvate-d3

Modify Date: 2024-01-31 12:02:14

Ethyl pyruvate-d3 Structure
Ethyl pyruvate-d3 structure
Common Name Ethyl pyruvate-d3
CAS Number 66966-38-9 Molecular Weight 119.13400
Density N/A Boiling Point N/A
Molecular Formula C5H5D3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ethyl pyruvate-d3


Ethyl pyruvate-d3 is the deuterium labeled Ethyl pyruvate[1]. Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent[2].

 Names

Name ethyl pyruvate (3,3,3-d3)
Synonym More Synonyms

 Ethyl pyruvate-d3 Biological Activity

Description Ethyl pyruvate-d3 is the deuterium labeled Ethyl pyruvate[1]. Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Fink MP. Ethyl pyruvate: a novel anti-inflammatory agent. J Intern Med. 2007 Apr;261(4):349-62.  

[3]. Olcum M, Tufekci KU, Durur DY, et al. Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling. Antioxidants (Basel). 202110(5):745.  

 Chemical & Physical Properties

Molecular Formula C5H5D3O3
Molecular Weight 119.13400
Exact Mass 119.06600
PSA 43.37000
LogP 0.13850

 Synonyms

Ethyl-pyruvat-d3
Ethyl-pyridyl-4-ketimin
Ethyl-pyrid-4-yl-ketimin
PYRIDINE,4-PROPIONIMIDOYL
3,3,3-trideuterio-2-oxo-propionic acid ethyl ester
1-pyridin-4-yl-propylideneamine