Benzenesulfonamide, 4-(hydroxymethyl)- (9CI)

Modify Date: 2026-07-04 12:14:05

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure
Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) structure
Common Name Benzenesulfonamide, 4-(hydroxymethyl)- (9CI)
CAS Number 67472-44-0 Molecular Weight 187.21600
Density 1.416±0.06 g/cm3 Boiling Point 406.2±47.0℃
Molecular Formula C7H9NO3S Melting Point 119-120℃
MSDS N/A Flash Point N/A

 Names

Name 4-(hydroxymethyl)benzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.416±0.06 g/cm3
Boiling Point 406.2±47.0℃
Melting Point 119-120℃
Molecular Formula C7H9NO3S
Molecular Weight 187.21600
Exact Mass 187.03000
PSA 88.77000
LogP 1.60740
InChIKey UULCVOIRJRJPQS-UHFFFAOYSA-N
SMILES NS(=O)(=O)c1ccc(CO)cc1
Storage condition 2-8℃

 Synthetic Route

~72%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

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Literature: G.D. Searle and Co. Patent: US5935990 A1, 1999 ;

~74%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

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Literature: Procopiou, Panayiotis A.; Barrett, Victoria J.; Bevan, Nicola J.; Biggadike, Keith; Box, Philip C.; Butchers, Peter R.; Coe, Diane M.; Conroy, Richard; Emmons, Amanda; Ford, Alison J.; Holmes, Duncan S.; Horsley, Helen; Kerr, Fern; Li-Kwai-Cheung, Anne-Marie; Looker, Brian E.; Mann, Inderjit S.; McLay, Iain M.; Morrison, Valerie S.; Mutch, Peter J.; Smith, Claire E.; Tomlin, Paula Journal of Medicinal Chemistry, 2010 , vol. 53, # 11 p. 4522 - 4530

~92%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

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Literature: Yang, Li-Ming; Lin, Shwu-Jiuan; Hsu, Fen-Lin; Yang, Tsang-Hsiung Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 7 p. 1013 - 1015

~%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

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Literature: Botre, Claudio; Botre, Francesco; Jommi, Giancarlo; Signorini, Roberto Journal of Medicinal Chemistry, 1986 , vol. 29, # 10 p. 1814 - 1820

~%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

Learn More
Literature: Yang, Li-Ming; Lin, Shwu-Jiuan; Hsu, Fen-Lin; Yang, Tsang-Hsiung Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 7 p. 1013 - 1015

~%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

Learn More
Literature: Yang, Li-Ming; Lin, Shwu-Jiuan; Hsu, Fen-Lin; Yang, Tsang-Hsiung Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 7 p. 1013 - 1015

~%

Benzenesulfonamide, 4-(hydroxymethyl)- (9CI) Structure

Benzenesulfonam...

CAS#:67472-44-0

Learn More
Literature: Koetschet; Koetschet Helvetica Chimica Acta, 1929 , vol. 12, p. 696

 Bioassay

View more

Name: Inhibition of human recombinant CA 3 assessed as CO2 hydration by stopped flow kineti...
Source: ChEMBL
Target: Carbonic anhydrase 3
External Id: CHEMBL898699
Name: Inhibition of GST-tagged astrosclera willeyana Astrosclerin-3 expressed in Escherichi...
Source: ChEMBL
Target: Carbonic anhydrase
External Id: CHEMBL1947439
Name: Inhibition of Vibrio cholerae alpha-carbonic anhydrase using CO2 as substrate preincu...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3761240
Name: Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO...
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL1947441
Name: Inhibition of Vibrio cholerae beta-carbonic anhydrase using CO2 as substrate preincub...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3760464
Name: Inhibitory constant against catalytic domain of human carbonic anhydrase XII
Source: ChEMBL
Target: Carbonic anhydrase 12
External Id: CHEMBL827186
Name: Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO...
Source: ChEMBL
Target: Carbonic anhydrase 1
External Id: CHEMBL1947440
Name: Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mi...
Source: ChEMBL
Target: Carbonic anhydrase 1
External Id: CHEMBL3761242
Name: Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mi...
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL3761241
Name: Inhibitory activity against Human carbonic anhydrase II
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL658042
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 Synonyms

4-hydroxymethyl-benzenesulfonic acid amide
aromatic/heteroaromatic sulfonamide 21
4-hydroxymethyl-benzene-sulphonamide
4-Hydroxymethyl-benzolsulfonsaeure-amid
4-Hydroxymethyl-benzenesulfonamide
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