Dehydrotumulosic acid

Modify Date: 2026-07-24 10:11:32

Dehydrotumulosic acid Structure
Dehydrotumulosic acid structure
Common Name Dehydrotumulosic acid
CAS Number 6754-16-1 Molecular Weight 484.71000
Density 1.11±0.1 g/cm3 Boiling Point 621.7±55.0 °C
Molecular Formula C31H48O4 Melting Point 272-275°C
MSDS N/A Flash Point N/A

 Use of Dehydrotumulosic acid


Dehydrotumulosic acid, one of the effective constituents of Poria cocos, was isolated from the chloroform-soluble material of ethanol extract of the fungus. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body[1].

 Names

Name Dehydrotumulosic acid

 Dehydrotumulosic acid Biological Activity

Description Dehydrotumulosic acid, one of the effective constituents of Poria cocos, was isolated from the chloroform-soluble material of ethanol extract of the fungus. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body[1].
Related Catalog
References

[1]. Song Z, et al. The isolation, identification and determination of dehydrotumulosic acid in Poria cocos. Anal Sci. 2002 May;18(5):529-31.

 Chemical & Physical Properties

Density 1.11±0.1 g/cm3
Boiling Point 621.7±55.0 °C
Melting Point 272-275°C
Molecular Formula C31H48O4
Molecular Weight 484.71000
Exact Mass 484.35500
PSA 77.76000
LogP 6.53660
InChIKey LADJWZMBZBVBSB-UHFFFAOYSA-N
SMILES C=C(CCC(C(=O)O)C1C(O)CC2(C)C3=CCC4C(C)(CCC(O)C4(C)C)C3=CCC12C)C(C)C
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Dehydrotumulosic acidBioassay

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Name: Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay
Source: ChEMBL
Target: CCRF-CEM
External Id: CHEMBL3994836
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Target: Acidic phospholipase A2 2
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Source: ChEMBL
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Source: ChEMBL
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Source: ChEMBL
Target: Raji
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Source: ChEMBL
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Name: Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: K562
External Id: CHEMBL3994838
Name: Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: HL-60
External Id: CHEMBL3994837
Name: Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activati...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1012198
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