2'-Hydroxy-5'-trifluoromethylacetophenone

Modify Date: 2024-01-10 19:04:17

2'-Hydroxy-5'-trifluoromethylacetophenone Structure
2'-Hydroxy-5'-trifluoromethylacetophenone structure
Common Name 2'-Hydroxy-5'-trifluoromethylacetophenone
CAS Number 67589-15-5 Molecular Weight 204.14600
Density N/A Boiling Point 219.7±35.0°C
Molecular Formula C9H7F3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 219.7±35.0°C
Molecular Formula C9H7F3O2
Molecular Weight 204.14600
Exact Mass 204.04000
PSA 37.30000
LogP 2.61360
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synthetic Route

~78%

2'-Hydroxy-5'-trifluoromethylacetophenone Structure

2'-Hydroxy-5'-t...

CAS#:67589-15-5

Literature: Fujimoto, Tatsuhiko; Kunitomo, Jun; Tomata, Yoshihide; Marui, Shogo; Nishiyama, Keiji; Nakashima, Masato; Yoshikubo, Shin-Ichi; Hirai, Keisuke; Hirozane, Mariko Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6414 - 6416

~41%

2'-Hydroxy-5'-trifluoromethylacetophenone Structure

2'-Hydroxy-5'-t...

CAS#:67589-15-5

Literature: PFIZER PRODUCTS INC. Patent: WO2008/65508 A1, 2008 ; Location in patent: Page/Page column 24 ;

~%

2'-Hydroxy-5'-trifluoromethylacetophenone Structure

2'-Hydroxy-5'-t...

CAS#:67589-15-5

Literature: Central Glass Company, Limited Patent: US2003/109574 A1, 2003 ;

~%

2'-Hydroxy-5'-trifluoromethylacetophenone Structure

2'-Hydroxy-5'-t...

CAS#:67589-15-5

Literature: DOMAIN THERAPEUTICS; PRESTWICK CHEMICAL, INC.; SCHANN, Stephan; MAYER, Stanislas; MORICE, Christophe; GIETHLEN, Bruno Patent: WO2011/51478 A1, 2011 ; WO 2011/051478 A1

~62%

2'-Hydroxy-5'-trifluoromethylacetophenone Structure

2'-Hydroxy-5'-t...

CAS#:67589-15-5

Literature: Jimenez, M. Consuelo; Leal, Pablo; Miranda, Miguel A.; Tormos, Rosa Journal of the Chemical Society, Chemical Communications, 1995 , # 19 p. 2009 - 2010

~%

2'-Hydroxy-5'-trifluoromethylacetophenone Structure

2'-Hydroxy-5'-t...

CAS#:67589-15-5

Literature: Fujimoto, Tatsuhiko; Kunitomo, Jun; Tomata, Yoshihide; Marui, Shogo; Nishiyama, Keiji; Nakashima, Masato; Yoshikubo, Shin-Ichi; Hirai, Keisuke; Hirozane, Mariko Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6414 - 6416

 Synonyms

1-[2-Hydroxy-5-(trifluoromethyl)phenyl]ethanone