Hydrangel 8-O-glucoside

Modify Date: 2026-07-29 20:20:55

Hydrangel 8-O-glucoside structure	Common Name	Hydrangel 8-O-glucoside
	CAS Number	67600-94-6	Molecular Weight	418.39
	Density	1.5±0.1 g/cm3	Boiling Point	763.7±60.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₂O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	272.0±26.4 °C

Use of Hydrangel 8-O-glucoside

Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].

Name	3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-gluc opyranoside
Synonym	More Synonyms

Description	Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2. [2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254.

Description

Related Catalog

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

References

[1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2.

[2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254.

Density	1.5±0.1 g/cm3
Boiling Point	763.7±60.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₂O₉
Molecular Weight	418.39
Flash Point	272.0±26.4 °C
Exact Mass	418.126373
PSA	145.91000
LogP	-0.39
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.670
InChIKey	IKTPWMTZNXOEIV-VRKGAULQSA-N
SMILES	O=C1OC(c2ccc(O)cc2)Cc2cccc(OC3OC(CO)C(O)C(O)C3O)c21

Hazard Codes	Xi

Precursor 0
DownStream 1
CAS#:480-47-7 Hydrangenol

Name: Increase in triglyceride levels in mouse 3T3L1 cells at 10 uM
Source: ChEMBL
Target: 3T3-L1
External Id: CHEMBL923224

Name: Increase in triglyceride levels in mouse 3T3L1 cells at 30 uM
Source: ChEMBL
Target: 3T3-L1
External Id: CHEMBL923225

Name: Increase in triglyceride levels in mouse 3T3L1 cells at 100 uM
Source: ChEMBL
Target: 3T3-L1
External Id: CHEMBL923226

Name: Increase in triglyceride levels in mouse 3T3L1 cells at 1 uM
Source: ChEMBL
Target: 3T3-L1
External Id: CHEMBL923222

Name: Increase in triglyceride levels in mouse 3T3L1 cells at 3 uM
Source: ChEMBL
Target: 3T3-L1
External Id: CHEMBL923223

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3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-glucopyranoside

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China
Product Name: HYDRANGENOL 8-O-GLUCOSIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
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naturewill
China
Product Name: Hydrangel 8-O-glucoside
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

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