Hydrangel 8-O-glucoside

Modify Date: 2024-04-05 14:30:59

Hydrangel 8-O-glucoside Structure
Hydrangel 8-O-glucoside structure
Common Name Hydrangel 8-O-glucoside
CAS Number 67600-94-6 Molecular Weight 418.39
Density 1.5±0.1 g/cm3 Boiling Point 763.7±60.0 °C at 760 mmHg
Molecular Formula C21H22O9 Melting Point N/A
MSDS N/A Flash Point 272.0±26.4 °C

 Use of Hydrangel 8-O-glucoside


Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].

 Names

Name 3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-gluc opyranoside
Synonym More Synonyms

 Hydrangel 8-O-glucoside Biological Activity

Description Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].
Related Catalog
References

[1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2.  

[2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 763.7±60.0 °C at 760 mmHg
Molecular Formula C21H22O9
Molecular Weight 418.39
Flash Point 272.0±26.4 °C
Exact Mass 418.126373
PSA 145.91000
LogP -0.39
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.670

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

1H-2-Benzopyran-1-one, 8-(β-D-glucopyranosyloxy)-3,4-dihydro-3-(4-hydroxyphenyl)-
3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-glucopyranoside
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