Hydrangel 8-O-glucoside

Modify Date: 2024-04-05 14:30:59

Hydrangel 8-O-glucoside structure	Common Name	Hydrangel 8-O-glucoside
	CAS Number	67600-94-6	Molecular Weight	418.39
	Density	1.5±0.1 g/cm3	Boiling Point	763.7±60.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₂O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	272.0±26.4 °C

Use of Hydrangel 8-O-glucoside

Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].

Name	3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-gluc opyranoside
Synonym	More Synonyms

Description	Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. Hydrangenol 8-O-glucoside is an AChE inhibitor (IC50: 22.66 μM). Hydrangenol 8-O-glucoside inhibits passive cutaneous anaphylaxis (PCA) reaction[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2. [2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254.

Description

Related Catalog

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

References

[1]. Matsuda H, et al. Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol Pharm Bull. 1999 Aug;22(8):870-2.

[2]. Hwang J, et al. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):254.

Density	1.5±0.1 g/cm3
Boiling Point	763.7±60.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₂O₉
Molecular Weight	418.39
Flash Point	272.0±26.4 °C
Exact Mass	418.126373
PSA	145.91000
LogP	-0.39
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.670

Hazard Codes	Xi

Precursor 0
DownStream 1
CAS#:480-47-7 Hydrangenol

1H-2-Benzopyran-1-one, 8-(β-D-glucopyranosyloxy)-3,4-dihydro-3-(4-hydroxyphenyl)-

3-(4-Hydroxyphenyl)-1-oxo-3,4-dihydro-1H-isochromen-8-yl β-D-glucopyranoside

BioBioPha
China
Product Name: Hydrangel 8-O-glucoside
Price: ￥4250.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: HYDRANGENOL 8-O-GLUCOSIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Hydrangel 8-O-glucoside

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