Tetrahydro-11-deoxy Cortisol
Tetrahydro-11-deoxy Cortisol structure
|
Common Name | Tetrahydro-11-deoxy Cortisol | ||
|---|---|---|---|---|
| CAS Number | 68-60-0 | Molecular Weight | 350.49200 | |
| Density | 1.186g/cm3 | Boiling Point | 505.1ºC at 760 mmHg | |
| Molecular Formula | C21H34O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 273.4ºC | |
Use of Tetrahydro-11-deoxy CortisolTetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency[1][2]. |
| Name | 1-[(3R,5R,8R,9S,10S,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone |
|---|---|
| Synonym | More Synonyms |
| Description | Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1]. |
| References |
| Density | 1.186g/cm3 |
|---|---|
| Boiling Point | 505.1ºC at 760 mmHg |
| Molecular Formula | C21H34O4 |
| Molecular Weight | 350.49200 |
| Flash Point | 273.4ºC |
| Exact Mass | 350.24600 |
| PSA | 77.76000 |
| LogP | 2.68250 |
| Index of Refraction | 1.56 |
| InChIKey | UPTAPIKFKZGAGM-FAIYVORSSA-N |
| SMILES | CC12CCC(O)CC1CCC1C2CCC2(C)C1CCC2(O)C(=O)CO |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| Precursor 0 | |
|---|---|
| DownStream 2 | |
CAS#:846-46-8
CAS#:53-42-9|
Study of urinary steroid hormone disorders: difference between hepatocellular carcinoma in early stage and cirrhosis.
Anal. Bioanal. Chem 406(18) , 4325-35, (2014) Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Discovery of novel biomarkers for early HCC from other liver diseases such as cirrhosis is of great clinical benefit. In th... |
|
|
[Urinary tetrahydro-11-deoxycortisol].
Nihon Rinsho. 68 Suppl 7 , 401-3, (2010)
|
|
|
A quantitative in vivo mouse model used to assay inhibitors of tumor-induced angiogenesis.
Cancer Res. 51(4) , 1339-44, (1991) An in vivo model of tumor-induced angiogenesis was used to monitor two known inhibitors of angiogenesis, protamine sulfate and the steroid tetrahydro S. Tumor cells entrapped in alginate beads were in... |
|
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
|
|
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
|
| tetrahydrocortexolone |
| 5beta-Pregnane-3alpha,17alpha,21-triol-20-one |
| 3alpha,17alpha,21-Trihydroxy-5beta-pregnan-20-one |
| EINECS 200-691-0 |
| Tetrahydrodeoxycortisol |
| Tetrahydro-11-deoxycortisol |