Tetrahydro-11-deoxy Cortisol
Tetrahydro-11-deoxy Cortisol structure
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Common Name | Tetrahydro-11-deoxy Cortisol | ||
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| CAS Number | 68-60-0 | Molecular Weight | 350.49200 | |
| Density | 1.186g/cm3 | Boiling Point | 505.1ºC at 760 mmHg | |
| Molecular Formula | C21H34O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 273.4ºC | |
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Study of urinary steroid hormone disorders: difference between hepatocellular carcinoma in early stage and cirrhosis.
Anal. Bioanal. Chem 406(18) , 4325-35, (2014) Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Discovery of novel biomarkers for early HCC from other liver diseases such as cirrhosis is of great clinical benefit. In this study, a novel steroid hormone metabolomic method based ... |
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[Urinary tetrahydro-11-deoxycortisol].
Nihon Rinsho. 68 Suppl 7 , 401-3, (2010)
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A quantitative in vivo mouse model used to assay inhibitors of tumor-induced angiogenesis.
Cancer Res. 51(4) , 1339-44, (1991) An in vivo model of tumor-induced angiogenesis was used to monitor two known inhibitors of angiogenesis, protamine sulfate and the steroid tetrahydro S. Tumor cells entrapped in alginate beads were injected s.c. into mice. Blood vessel induction was measured ... |
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Potent inhibitory effects of steroids in an in vitro model of angiogenesis.
J. Endocrinol. 150(3) , 457-64, (1996) The regulation of angiogenesis in the ovarian follicle and corpus luteum is unclear. Steroids are produced at very high concentrations in these tissues and we therefore examined the effect of steroids on angiogenesis in vitro. Explants of rat aorta were embed... |
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In the ventral tegmental area, progestins' membrane-mediated actions for lordosis of hamsters and rats involve protein kinase A.
Neuroendocrinology 84(6) , 405-14, (2006) Progestin-facilitated lordosis of hamsters and rats is enhanced by activation of dopamine type 1 (D1) or GABAA/benzodiazepine receptor complexes (GBRs) in the ventral tegmental area (VTA) and these effects involve G-proteins and second messengers, such as ade... |
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Comprehensive study of urinary cortisol metabolites in hyperthyroid and hypothyroid patients.
Clin. Endocrinol. (Oxf.) 64(1) , 37-45, (2006) To further analyse the significance and mutual relationship of thyroid function-linked alterations in cortisol metabolism that have been separately and variously reported.Twenty-four-hour urine samples from 21 patients with hyperthyroidism (Graves' disease), ... |
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Aldosterone synthase gene variation and adrenocortical response to sodium status, angiotensin II and ACTH in normal male subjects.
Clin. Endocrinol. (Oxf.) 61(2) , 174-81, (2004) Aldosterone synthase, a key enzyme in the terminal steps of aldosterone synthesis, is encoded by the CYP11B2 gene. A polymorphism in the 5' coding region of this gene (-344 C/T) is associated with hypertension, particularly with elevation of the aldosterone t... |
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Heparin-steroid conjugates lacking glucocorticoid or mineralocorticoid activities inhibit the proliferation of vascular endothelial cells.
Biochim. Biophys. Acta 1310(1) , 86-96, (1996) A new class of angiogenesis inhibitors consist of a non-anticoagulating derivative of heparin, which binds to vascular endothelial cells, coupled to a steriod (e.g., cortisol) which suppresses endothelial cell division. We linked heparin to a further 10 stero... |
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Interference by danazol with the Porter-Silber method for determination of urinary 17-hydroxycorticosteroids.
Ann. Clin. Biochem. 38(Pt 3) , 277-9, (2001)
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Endogenous urinary steroids in premenopausal women with uterine leiomyomas.
Int. J. Gynaecol. Obstet. 84(1) , 55-60, (2004) To study the effect of endogenous steroids on the presence of uterine leiomyomas.Urine samples of 27 premenopausal women with leiomyomas and 25 age-matched healthy premenopausal women were collected. The concentration of estrogens and androgens in the urine s... |