Isoliensinine
Modify Date: 2024-01-05 11:00:53
Isoliensinine structure
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Common Name | Isoliensinine | ||
|---|---|---|---|---|
| CAS Number | 6817-41-0 | Molecular Weight | 610.739 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 723.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C37H42N2O6 | Melting Point | 69-71℃ | |
| MSDS | N/A | Flash Point | 391.1±32.9 °C | |
Use of IsoliensinineIsoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells[1][2]. |
| Name | (1R)-1-[[4-hydroxy-3-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol |
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| Synonym | More Synonyms |
| Description | Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells[1][2]. |
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| Related Catalog | |
| In Vitro | Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation[1]. Isoliensinine exerts antiproliferative effect on CASMCs induced by phenylephrine, and its mechanisms are related to decrease the overexpression of growth factors (PDGF-beta, bFGF), protooncogene (c-fos, c-myc) and hsp70[3]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 723.1±60.0 °C at 760 mmHg |
| Melting Point | 69-71℃ |
| Molecular Formula | C37H42N2O6 |
| Molecular Weight | 610.739 |
| Flash Point | 391.1±32.9 °C |
| Exact Mass | 610.304260 |
| PSA | 83.86000 |
| LogP | 4.72 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.618 |
| Storage condition | 2-8°C |
| Hazard Codes | Xn |
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| (1R)-1-(4-Hydroxy-3-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinyl]oxy}benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinol |
| Isoliensinin |
| (1R)-1-(4-Hydroxy-3-{[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol |
| 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-hydroxy-3-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenyl]methyl]-6-methoxy-2-methyl-, (1R)- |
| Isoliensinine |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Isoliensinine
- Price: ￥2378.0/20mg ￥538.0/10mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Isoliensinine
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
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Price: ￥500/1 mg
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