Cytostatin

Modify Date: 2024-01-14 12:55:20

Cytostatin Structure
Cytostatin structure
Common Name Cytostatin
CAS Number 682329-63-1 Molecular Weight 428.456
Density 1.2±0.1 g/cm3 Boiling Point 645.2±65.0 °C at 760 mmHg
Molecular Formula C21H33O7P Melting Point N/A
MSDS N/A Flash Point 344.0±34.3 °C

 Use of Cytostatin


Cytostatin is a potent and selective inhibitor of PP2A with promising antitumor activity. Cytostatin belongs to the fostriecin family of natural products[1].

 Names

Name (2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8,10,12-tetradecatrien-5-yl dihydrogen phosphate
Synonym More Synonyms

 Cytostatin Biological Activity

Description Cytostatin is a potent and selective inhibitor of PP2A with promising antitumor activity. Cytostatin belongs to the fostriecin family of natural products[1].
Related Catalog
Target

PP2A[1]

References

[1]. Lawhorn BG, et al. Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition. J Am Chem Soc. 2006;128(51):16720-16732.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 645.2±65.0 °C at 760 mmHg
Molecular Formula C21H33O7P
Molecular Weight 428.456
Flash Point 344.0±34.3 °C
Exact Mass 428.196381
LogP 2.28
Vapour Pressure 0.0±4.4 mmHg at 25°C
Index of Refraction 1.529

 Safety Information

Hazard Codes Xi

 Synonyms

(2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-8,10,12-tetradecatrien-5-yl dihydrogen phosphate
2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, (5S,6S)-
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Cytostatin suppliers

Cytostatin price