SKF 91488 dihydrochloride

Modify Date: 2024-04-05 19:33:47

SKF 91488 dihydrochloride structure	Common Name	SKF 91488 dihydrochloride
	CAS Number	68941-21-9	Molecular Weight	248.22
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇H₁₉Cl₂N₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SKF 91488 dihydrochloride

SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a Ki value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice[1].

Name	Homodimaprit dihydrochloride
Synonym	More Synonyms

Description	SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a Ki value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Histone Methyltransferase Research Areas >> Neurological Disease
References	[1]. Beaven MA, et, al. Inhibition of histamine methylation in vivo by the dimaprit analog, SKF Compound 91488. Agents Actions. 1979 Dec;9(5-6):455-60.

Molecular Formula	C₇H₁₉Cl₂N₃S
Molecular Weight	248.22
Exact Mass	211.09100
PSA	78.41000
LogP	2.55690

S-(4-dimethylamino-butyl)-isothiourea, dihydrochloride

S-(4-Dimethylamino-butyl)-isothioharnstoff, Dihydrochlorid

S-[4-(dimethylamino)butyl]isothiourea dihydrochloride

SKF 91488 dihydrochloride

Use of SKF 91488 dihydrochloride

Names

SKF 91488 dihydrochloride Biological Activity

Chemical & Physical Properties

Synonyms