5-Hydroxydiclofenac
5-Hydroxydiclofenac structure
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Common Name | 5-Hydroxydiclofenac | ||
|---|---|---|---|---|
| CAS Number | 69002-84-2 | Molecular Weight | 312.148 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 444.8±45.0 °C at 760 mmHg | |
| Molecular Formula | C14H11Cl2NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 222.8±28.7 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 5-hydroxydiclofenac |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 444.8±45.0 °C at 760 mmHg |
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.148 |
| Flash Point | 222.8±28.7 °C |
| Exact Mass | 311.011597 |
| PSA | 69.56000 |
| LogP | 3.91 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.690 |
| InChIKey | VNQURRWYKFZKJZ-UHFFFAOYSA-N |
| SMILES | O=C(O)Cc1cc(O)ccc1Nc1c(Cl)cccc1Cl |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335-H410 |
| Precautionary Statements | P273-P280-P301 + P312 + P330-P337 + P313-P391-P501 |
| RIDADR | UN 3077 9 / PGIII |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 1 | |
CAS#:15307-86-5![2-[2-(2,6-dichloroanilino)-5-hydroxyphenyl]-N,N-dimethylacetamide Structure](https://image.chemsrc.com/caspic/246/698357-97-0.png)
CAS#:698357-97-0
CAS#:15307-79-6
CAS#:30267-40-4
CAS#:30124-19-7
CAS#:90526-08-2
CAS#:99540-20-2![2-[2-(2,6-dichloroanilino)-5-methoxyphenyl]-N,N-dimethylacetamide Structure](https://image.chemsrc.com/caspic/446/698357-92-5.png)
CAS#:698357-92-5
CAS#:100-02-7This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Glutathione reactivity of the compound assessed as GSH-adduct formation at 0.5 mg/ml ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5166495
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Name: Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cerebral cortex membrane hom...
Source: ChEMBL
Target: Calcium/calmodulin-dependent protein kinase type II subunit alpha
External Id: CHEMBL5166478
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Name: Inhibition of COX (unknown origin)
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL2432168
|
|
Name: Inhibition of inflammatory hind paw edema, induced by Mycobacterium butyricum in rats...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL797721
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Name: In vitro inhibition of bovine prostaglandin G/H synthase, using bovine seminal vesicl...
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL858257
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Name: Displacement of [3H]NCS-382 from CaMK2alpha in rat brain cortical membrane homogenate...
Source: ChEMBL
Target: Calcium/calmodulin-dependent protein kinase type II subunit alpha
External Id: CHEMBL5099988
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Name: Displacement of [3H]HOCPCA from native CaMK2alpha in rat brain cortical membrane homo...
Source: ChEMBL
Target: Calcium/calmodulin-dependent protein kinase type II subunit alpha
External Id: CHEMBL5099989
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Name: Displacement of [3H]HOCPCA from recombinant rat CaMK2alpha expressed in HEK293T cells...
Source: ChEMBL
Target: Calcium/calmodulin-dependent protein kinase type II subunit alpha
External Id: CHEMBL5099990
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5-Hydroxydiclofenac |
| 5-OH DCF |
| {2-[(2,6-Dichlorophenyl)amino]-5-hydroxyphenyl}acetic acid |
| 2-[2-(2,6-dichloroanilino)-5-hydroxyphenyl]acetic acid |
| 5-hydroxydiclophenac |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the downstream products of 5-hydroxydiclofenac? |
| A: Related downstream products(CAS) of 5-hydroxydiclofenac: 30267-40-4. |
| Q: What is the polar surface area (PSA) of 5-hydroxydiclofenac? |
| A: Polar surface area (PSA) of 5-hydroxydiclofenac is 69.56000. |
| Q: What is the SMILES notation of 5-hydroxydiclofenac? |
| A: SMILES notation of 5-hydroxydiclofenac is O=C(O)Cc1cc(O)ccc1Nc1c(Cl)cccc1Cl. |
| Q: What English synonyms does 5-hydroxydiclofenac have? |
| A: English synonyms of 5-hydroxydiclofenac: 5-Hydroxydiclofenac, 5-OH DCF, {2-[(2,6-Dichlorophenyl)amino]-5-hydroxyphenyl}acetic acid, 2-[2-(2,6-dichloroanilino)-5-hydroxyphenyl]acetic acid, 5-hydroxydiclophenac. |
| Q: What is the molecular formula of 5-hydroxydiclofenac? |
| A: Molecular formula of 5-hydroxydiclofenac is C14H11Cl2NO3. |
| Q: What is the LogP of 5-hydroxydiclofenac? |
| A: LogP of 5-hydroxydiclofenac is 3.91. |
| Q: What is the boiling point of 5-hydroxydiclofenac? |
| A: Boiling point of 5-hydroxydiclofenac is 444.8±45.0 °C at 760 mmHg. |
| Q: What is the CAS number of 5-hydroxydiclofenac? |
| A: CAS number of 5-hydroxydiclofenac is 69002-84-2. |
| Q: What is the molecular weight of 5-hydroxydiclofenac? |
| A: Molecular weight of 5-hydroxydiclofenac is 312.148. |
| Q: What are the upstream materials of 5-hydroxydiclofenac? |
| A: Related upstream materials(CAS) of 5-hydroxydiclofenac: 15307-86-5;698357-97-0;15307-79-6;30267-40-4;30124-19-7;90526-08-2;99540-20-2;698357-92-5;100-02-7. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |