Harpagide
Modify Date: 2025-08-25 21:57:01
Harpagide structure
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Common Name | Harpagide | ||
|---|---|---|---|---|
| CAS Number | 6926-08-5 | Molecular Weight | 364.345 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 637.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H24O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 339.1±31.5 °C | |
Use of HarpagideHarpagide is a class of iridoid glycoside isolated from Scrophularia cryptophila and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2]. |
| Name | Harpagide |
|---|---|
| Synonym | More Synonyms |
| Description | Harpagide is a class of iridoid glycoside isolated from Scrophularia cryptophila and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Harpagide shows cytotoxic activity over 50% in a concentration of 90 μg/mL, Harpagide on the A431 and HeLa cell lines. The cytotoxic effect of Harpagide on the MCF7 cell line in a concentration of 90 μg/mL[3]. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 637.1±55.0 °C at 760 mmHg |
| Molecular Formula | C15H24O10 |
| Molecular Weight | 364.345 |
| Flash Point | 339.1±31.5 °C |
| Exact Mass | 364.136932 |
| PSA | 169.30000 |
| LogP | -3.69 |
| Vapour Pressure | 0.0±4.3 mmHg at 25°C |
| Index of Refraction | 1.663 |
| Safety Phrases | 24/25 |
|---|
|
~70%
Harpagide CAS#:6926-08-5 |
| Literature: Weinges, Klaus; Zourari, Maria; Smuda, Hubert; Rodewald, Hans; Nixdorf, Matthias; Irngartinger, Hermann Liebigs Annalen der Chemie, 1985 , # 5 p. 1063 - 1081 |
|
~%
Harpagide CAS#:6926-08-5 |
| Literature: Chemical & Pharmaceutical Bulletin, , vol. 31, # 7 p. 2296 - 2301 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 4a,5,7-Trihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl hexopyranoside |
| einecs 230-050-0 |
| Hexopyranoside, 1,4a,5,6,7,7a-hexahydro-4a,5,7-trihydroxy-7-methylcyclopenta[c]pyran-1-yl |
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