8-O-Acetylharpagide

Modify Date: 2024-01-03 18:20:35

8-O-Acetylharpagide structure	Common Name	8-O-Acetylharpagide
	CAS Number	6926-14-3	Molecular Weight	406.382
	Density	1.6±0.1 g/cm3	Boiling Point	607.2±55.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₆O₁₁	Melting Point	227-229℃
	MSDS	USA	Flash Point	215.9±25.0 °C

Use of 8-O-Acetylharpagide

8-O-Acetylharpagide is an iridoid isolated from Ajuga reptans with antitumoral, antiviral, antibacterial, and anti-inflammatory activities. 8-O-Acetylharpagide also has a biological activity on isolated smooth muscle preparations from guinea pig[1][2].

Name	8-O-Acetylharpagide
Synonym	More Synonyms

Description	8-O-Acetylharpagide is an iridoid isolated from Ajuga reptans with antitumoral, antiviral, antibacterial, and anti-inflammatory activities. 8-O-Acetylharpagide also has a biological activity on isolated smooth muscle preparations from guinea pig[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Wen B, et al. Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens Thunb extract in rats. J Ethnopharmacol. 2013 May 20;147(2):503-8. [2]. Breschi MC, et al. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans. J Nat Prod. 1992 Aug;55(8):1145-8.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Wen B, et al. Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens Thunb extract in rats. J Ethnopharmacol. 2013 May 20;147(2):503-8.

[2]. Breschi MC, et al. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans. J Nat Prod. 1992 Aug;55(8):1145-8.

Density	1.6±0.1 g/cm3
Boiling Point	607.2±55.0 °C at 760 mmHg
Melting Point	227-229℃
Molecular Formula	C₁₇H₂₆O₁₁
Molecular Weight	406.382
Flash Point	215.9±25.0 °C
Exact Mass	406.147522
PSA	175.37000
LogP	-3.48
Vapour Pressure	0.0±3.9 mmHg at 25°C
Index of Refraction	1.624
Storage condition	?20°C

Safety Phrases	24/25
RIDADR	NONH for all modes of transport

[Pharmacokinetics of 8-O-acetylharpagide and harpagide after oral administration of Ajuga decumbens extract in beagle dog].

Zhongguo Zhong Yao Za Zhi 38(12) , 2015-8, (2013)

8-O-acetylharpagide and harpagide are two kinds of effective component of Ajuga decumbens extract. A sensitive LC-MS/MS method has been established for pharmacokinetics of 8-O-acetylharpagide and harp...

[Determination of acetylharpagide in Ajuga decumbens by HPLC].

Zhongguo Zhong Yao Za Zhi 31(4) , 289-90, (2006)

To establish a method of the quantitative determination of acetylharpagide in Ajuga decumbens.The chromatographic conditions were as follows: a Phenomenex Luna C18 column was used, the mobile phase wa...

[Studies on chemical constituents of Galeopsis bifida].

Zhongguo Zhong Yao Za Zhi 27(3) , 206-8, (2002)

To investigate the chemical constituents of Galeopsis bifida.Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chem...

β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-7-(acetyloxy)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methylcyclopenta[c]pyran-1-yl

6-Thio-8-propylthiotheophylline

(1S,4aS,5R,7S,7aS)-1-(β-D-Glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl acetate

8-O-acetyl-harpagide

Harpagide 7-acetyl

Uric acid,1,3-dimethyl-8-propylthio-6-thio

8-n-Propylthio-6-thiotheophyllin