3-O-cis-p-Coumaroylmaslinic acid

Modify Date: 2024-04-02 11:52:27

3-O-cis-p-Coumaroylmaslinic acid Structure
3-O-cis-p-Coumaroylmaslinic acid structure
Common Name 3-O-cis-p-Coumaroylmaslinic acid
CAS Number 69297-40-1 Molecular Weight 618.843
Density 1.2±0.1 g/cm3 Boiling Point 715.6±60.0 °C at 760 mmHg
Molecular Formula C39H54O6 Melting Point 278-282 °C
MSDS N/A Flash Point 214.5±26.4 °C

 Use of 3-O-cis-p-Coumaroylmaslinic acid


3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].

 Names

Name 3-beta-O-(cis-p-Coumaroyl)maslinic acid
Synonym More Synonyms

 3-O-cis-p-Coumaroylmaslinic acid Biological Activity

Description 3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].
Related Catalog
Target

0.46 μM (PTP1B)[1]

References

[1]. de Cássia Lemos Lima R, et al. High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules. 2018;23(7):1755.  

[2]. Braca A, et al. Antimicrobial triterpenoids from Licania heteromorpha. Planta Med. 2000;66(8):768-769.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 715.6±60.0 °C at 760 mmHg
Melting Point 278-282 °C
Molecular Formula C39H54O6
Molecular Weight 618.843
Flash Point 214.5±26.4 °C
Exact Mass 618.392029
LogP 9.85
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.597

 Synonyms

Olean-12-en-28-oic acid, 2-hydroxy-3-[[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-, (2α,3β)-
(2α,3β)-2-Hydroxy-3-{[(2Z)-3-(4-hydroxyphenyl)-2-propenoyl]oxy}olean-12-en-28-oic acid