2-(4-hydroxyphenyl)quinoline-4-carboxylic acid

Modify Date: 2026-07-01 09:32:27

2-(4-hydroxyphenyl)quinoline-4-carboxylic acid Structure
2-(4-hydroxyphenyl)quinoline-4-carboxylic acid structure
Common Name 2-(4-hydroxyphenyl)quinoline-4-carboxylic acid
CAS Number 6952-34-7 Molecular Weight 265.26300
Density 1.374g/cm3 Boiling Point 500.997ºC at 760 mmHg
Molecular Formula C16H11NO3 Melting Point N/A
MSDS N/A Flash Point 256.794ºC

 Names

Name 2-(4-oxocyclohexa-2,5-dien-1-ylidene)-1H-quinoline-4-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.374g/cm3
Boiling Point 500.997ºC at 760 mmHg
Molecular Formula C16H11NO3
Molecular Weight 265.26300
Flash Point 256.794ºC
Exact Mass 265.07400
PSA 70.42000
LogP 3.30560
Index of Refraction 1.712
InChIKey KXZJHVJKXJLBKO-UHFFFAOYSA-N
SMILES O=C(O)c1cc(-c2ccc(O)cc2)nc2ccccc12

 Safety Information

HS Code 2933499090

 Synthetic Route

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2-(4-hydroxyphenyl)quinoline-4-carboxylic acid Structure

2-(4-hydroxyphe...

CAS#:6952-34-7

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Literature: DE284233 ;

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2-(4-hydroxyphenyl)quinoline-4-carboxylic acid Structure

2-(4-hydroxyphe...

CAS#:6952-34-7

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Literature: Wang, Li-Min; Hu, Liang; Chen, Hong-Juan; Sui, Yuan-Yuan; Shen, Wei Journal of Fluorine Chemistry, 2009 , vol. 130, # 4 p. 406 - 409

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2-(4-hydroxyphenyl)quinoline-4-carboxylic acid Structure

2-(4-hydroxyphe...

CAS#:6952-34-7

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Literature: Yakugaku Zasshi, , vol. 50, p. 235,238; dtsch. Ref. S. 31 Chem.Abstr., , p. 3511

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Primary cell-based high-throughput screening for identification of compounds that all...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_AlloAgonist_Primary
Name: Primary cell-based high-throughput screening for identification of compounds that ant...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_Antagonist_Primary
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: High throughput screen for small molecule inhibitors of a hypoxia-regulated fluoresce...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1149-MLP
Name: uHTS identification of small molecule inhibitors of tim10-1 yeast via a luminescent a...
Source: Burnham Center for Chemical Genomics
Target: TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [Saccharomyces cerevisiae S288c]
External Id: SBCCG-A413-tim10-1-Primary-Antagonist-Assay
Name: 384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC
Source: University of Pittsburgh Molecular Library Screening Center
Target: N/A
External Id: MH083223 Targeting HIV-1 Nef with Small Molecules
Name: uHTS identification of APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based sin...
Source: Burnham Center for Chemical Genomics
Target: probable DNA dC->dU-editing enzyme APOBEC-3A [Homo sapiens]
External Id: SBCCG-A539-APOBEC3A-Inhibitor-Primary-Assay
Name: High Throughput Screen to Identify Inhibitors Targeting HIV-1 Vif-dependent Degradati...
Source: Southern Research Institute
Target: HIV-1 Vif
External Id: HIV1-VIF_MS
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 Synonyms

cinchoninsaeure
2-(4-Hydroxy-phenyl)-quinoline-4-carboxylic acid
2-<4-Hydroxy-phenyl>-4-carboxy-chinolin
MFCD00687527
4-Carboxy-2-<4-hydroxy-phenyl>chinolin
2-(4-Hydroxy-phenyl)-chinolin-4-carbonsaeure
2-(2-METHYLVALERYL)OXAZOLE
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