Thymopentin structure
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Common Name | Thymopentin | ||
|---|---|---|---|---|
| CAS Number | 69558-55-0 | Molecular Weight | 679.765 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C30H49N9O9 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of ThymopentinThymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs)[1][2]. |
| Name | Thymopentin |
|---|---|
| Synonym | More Synonyms |
| Description | Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs)[1][2]. |
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| Related Catalog | |
| In Vitro | Thymopentin enhances the generation of T-cell lineage derived from hESCs in vitro [1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C30H49N9O9 |
| Molecular Weight | 679.765 |
| Exact Mass | 679.365295 |
| PSA | 325.17000 |
| LogP | -0.89 |
| Index of Refraction | 1.636 |
| InChIKey | PSWFFKRAVBDQEG-YGQNSOCVSA-N |
| SMILES | CC(C)C(NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(N)CCCN=C(N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Stability and aerosolization of pressurized metered dose inhalers containing thymopentin nanoparticles produced using a bottom-up process.
Int. J. Pharm. 427(2) , 385-92, (2012) The objective of this study was to investigate the stability and aerosolization of pressurized metered dose inhalers (pMDIs) containing thymopentin nanoparticles. Thymopentin nanoparticles, fabricated... |
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Separation and purification of thymopentin with molecular imprinting membrane by solid phase extraction disks.
J. Pharm. Biomed. Anal. 102 , 137-43, (2014) The synthesis and performance of molecularly imprinted membranes (MIMs) as a solid phase extraction packing materials for the separation and purification of thymopentin from crude samples was describe... |
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[Vulvar lesions caused by Papillomavirus (HPV): effectiveness of thymopentin (Syntomoduline). First results and experiences].
Minerva Ginecol. 43(1-2) , 53-6, (1991) The study included two different sized groups of patients suffering from various degrees of valvular microcondylomatosis. A group of 40 patients was treated using combined therapy while a second group... |
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291801
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Name: Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291798
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL5291791
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Binding efficacy expressed as counts remaining after competition was subtracted from ...
Source: ChEMBL
Target: CCRF-CEM
External Id: CHEMBL653907
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Name: Ability to bound CEM cell measured as competition for displacement of radiolabeled Th...
Source: ChEMBL
Target: CCRF-CEM
External Id: CHEMBL660064
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Name: Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay
Source: 24386
Target: N/A
External Id: Sarm1 Tir NADase inhibitors screen
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Name: Binding affinity towards human EDNRA in an in vitro assay with cellular components me...
Source: ChEMBL
Target: Endothelin-1 receptor
External Id: CHEMBL5291785
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| TP-5 |
| RKDVY |
| THYMOPENTIN 5 |
| Thymopentin |
| Arg-Lys-Asp-Val-Tyr |
| thymopoietin |
| MFCD00214200 |
| N-[N-[N-(N2-L-Arginyl-L-lysyl)-L-a-aspartyl]-L-valyl]-L-tyrosine |
| THYMOPETIN |
| L-Arginyl-L-lysyl-L-α-aspartyl-L-valyl-L-tyrosine |
| thymopoietin fragment 32-36 |
| Timunox |
| HArgLysAspValTyrOH |
| Immunox |
| N-(diaminomethylidene)-L-ornithyl-L-lysyl-L-α-aspartyl-L-valyl-L-tyrosine |
| Thymopoietin 32-36 |
| THYMOPOIETIN PENTAPEPTIDE |
| Sintomodulina |