2',3'-Dihydroxy-4'-methoxyacetophenone

Modify Date: 2024-01-04 19:38:36

2',3'-Dihydroxy-4'-methoxyacetophenone Structure
2',3'-Dihydroxy-4'-methoxyacetophenone structure
Common Name 2',3'-Dihydroxy-4'-methoxyacetophenone
CAS Number 708-53-2 Molecular Weight 182.173
Density 1.3±0.1 g/cm3 Boiling Point 359.6±42.0 °C at 760 mmHg
Molecular Formula C9H10O4 Melting Point 133ºC
MSDS N/A Flash Point 147.7±21.4 °C

 Use of 2',3'-Dihydroxy-4'-methoxyacetophenone


2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1].

 Names

Name 1-(2,3-dihydroxy-4-methoxyphenyl)ethanone
Synonym More Synonyms

 2',3'-Dihydroxy-4'-methoxyacetophenone Biological Activity

Description 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1].
Related Catalog
In Vitro 2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity[1].
In Vivo 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1].
References

[1]. Jin Bae Weon, et al. The Ameliorating Effects of 2,3-dihydroxy-4-methoxyacetophenone on Scopolamine-Induced Memory Impairment in Mice and Its Neuroprotective Activity. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6732-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 359.6±42.0 °C at 760 mmHg
Melting Point 133ºC
Molecular Formula C9H10O4
Molecular Weight 182.173
Flash Point 147.7±21.4 °C
Exact Mass 182.057907
PSA 66.76000
LogP 1.81
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.573

 Safety Information

HS Code 2914509090

 Synthetic Route

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

2,3-Dihydroxy-4-methoxy-acetophenon
Gallacetophenone-4'-methyl Ether
2,3-dihydroxy-4-methoxyacetophenone
1-acetyl-2,3-dihydroxy-4-methoxybenzene
Ethanone, 1-(2,3-dihydroxy-4-methoxyphenyl)-
MFCD00180772
1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone
1-(2,3-DIHYDROXY-4-METHOXYPHENYL)-ETHANONE