3'-Deoxy-5-methyluridine

Modify Date: 2024-01-10 19:29:27

3'-Deoxy-5-methyluridine Structure
3'-Deoxy-5-methyluridine structure
Common Name 3'-Deoxy-5-methyluridine
CAS Number 7084-29-9 Molecular Weight 242.23
Density 1.5±0.1 g/cm3 Boiling Point 530.01 °C(Predicted)
Molecular Formula C10H14N2O5 Melting Point 226.62 °C
MSDS N/A Flash Point N/A

 Use of 3'-Deoxy-5-methyluridine


3’-Deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym More Synonyms

 3'-Deoxy-5-methyluridine Biological Activity

Description 3’-Deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 530.01 °C(Predicted)
Melting Point 226.62 °C
Molecular Formula C10H14N2O5
Molecular Weight 242.23
Exact Mass 242.090271
PSA 104.55000
LogP -1.16
Index of Refraction 1.584

 Synonyms

3'-Deoxy-5-methyluridine
5-methyl-3'-deoxy-uridine
3'-deoxythymidine
Uridine, 3'-deoxy-5-methyl-
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