2-Ethyl-2-phenylmalonamide

Modify Date: 2024-01-02 20:35:28

2-Ethyl-2-phenylmalonamide Structure
2-Ethyl-2-phenylmalonamide structure
Common Name 2-Ethyl-2-phenylmalonamide
CAS Number 7206-76-0 Molecular Weight 206.24100
Density 1.183 g/cm3 Boiling Point 440.9ºC at 760 mmHg
Molecular Formula C11H14N2O2 Melting Point 120ºC
MSDS N/A Flash Point 113 °C

 Names

Name 2-Ethyl-2-phenylmalonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.183 g/cm3
Boiling Point 440.9ºC at 760 mmHg
Melting Point 120ºC
Molecular Formula C11H14N2O2
Molecular Weight 206.24100
Flash Point 113 °C
Exact Mass 206.10600
PSA 86.18000
LogP 1.70560
Storage condition Refrigerator
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility <0.01 g/100 mL at 18 ºC

 MSDS

Name: 2-Ethyl-2-Phenylmalonamide Monohydrate 99% Material Safety Data Sheet
Synonym: None
CAS: 7206-76-0
Section 1 - Chemical Product MSDS Name:2-Ethyl-2-Phenylmalonamide Monohydrate 99% Material Safety Data Sheet
Synonym:None

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
7206-76-0 2-Ethyl-2-Phenylmalonamide Monohydrate 99 230-583-9
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7206-76-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white to off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 120 deg C
Autoignition Temperature: Not available.
Flash Point: > 112 deg C (> 233.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C11H14N2O2.H2O
Molecular Weight: 224.26

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7206-76-0: RY0820000 LD50/LC50:
Not available.
Carcinogenicity:
2-Ethyl-2-Phenylmalonamide Monohydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7206-76-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 7206-76-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7206-76-0 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RY0820000
CHEMICAL NAME :
Propanediamide, 2-ethyl-2-phenyl-
CAS REGISTRY NUMBER :
7206-76-0
BEILSTEIN REFERENCE NO. :
1966103
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H14-N2-O2
MOLECULAR WEIGHT :
206.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 mg/plate
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988

 Safety Information

Safety Phrases S24/25
RIDADR NONH for all modes of transport

 Synthetic Route

~68%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: Lafont; Cave; Menager; Miocque European Journal of Medicinal Chemistry, 1990 , vol. 25, # 1 p. 61 - 66

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2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: European Journal of Medicinal Chemistry, , vol. 25, # 1 p. 61 - 66

~%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: DE310426 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 13, p. 802

~%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 14, # 1-2 p. 1 - 3

~%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: Helvetica Chimica Acta, , vol. 42, p. 2370,2375

~%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: Arzneimittel Forschung, , vol. 8, p. 44,46 Acta Academiae Aboensis, Series B: Mathematica et Physica, , vol. 20, # 4 p. 1,14 Chem.Abstr., , # 11352

~%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: Helvetica Chimica Acta, , vol. 42, p. 2370,2375

~%

2-Ethyl-2-phenylmalonamide Structure

2-Ethyl-2-pheny...

CAS#:7206-76-0

Literature: Arzneimittel-Forschung/Drug Research, , vol. 34, # 12 p. 1753 - 1757

 Synonyms

Aethyl-phenyl-malonsaeure-diamid
Malonamide,2-ethyl-2-phenyl
ethyl-phenyl-malonic acid diamide
Phenylethylmalondiamide
2-Ethyl-2-phenylmalondiamide
EINECS 230-583-9
Phenylethylmalonamide
Ethylphenylmalondiamide
PEMA
2-ethyl-2-phenyl-malonamid
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