2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

Modify Date: 2025-08-22 10:48:45

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine Structure
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine structure
Common Name 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
CAS Number 72537-17-8 Molecular Weight 199.533
Density 1.5±0.1 g/cm3 Boiling Point 155.2±35.0 °C at 760 mmHg
Molecular Formula C6H2ClF4N Melting Point 16-20 °C(lit.)
MSDS Chinese USA Flash Point 47.7±25.9 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Names

Name 3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 155.2±35.0 °C at 760 mmHg
Melting Point 16-20 °C(lit.)
Molecular Formula C6H2ClF4N
Molecular Weight 199.533
Flash Point 47.7±25.9 °C
Exact Mass 198.981186
PSA 12.89000
LogP 3.07
Vapour Pressure 3.9±0.3 mmHg at 25°C
Index of Refraction 1.430

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R10;R36/37/38
Safety Phrases S26-S36
RIDADR UN 1993 3/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 3.2
HS Code 2933399090

 Synthetic Route

~99%

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine Structure

2-fluoro-3-chlo...

CAS#:72537-17-8

Literature: Pfleger, Christophe; Waldmeier, Pius; Wang, Shaoning Patent: US2008/221327 A1, 2008 ; Location in patent: Page/Page column 9-10 ;

~10%

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine Structure

2-fluoro-3-chlo...

CAS#:72537-17-8

Literature: Yoneda; Fukuhara Tetrahedron, 1996 , vol. 52, # 1 p. 23 - 36

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

More Articles
Catalytic fluorination of 2-chloropyridine over metal oxide catalysts in gas phase in the presence of HF. Cochon C, et al.

Appl. Catal. A Gen. 413 , 149-156, (2012)

Regioselective substitution in aromatic six-membered nitrogen heterocycles. Comins DL and O'Connor S.

Adv. Heterocycl. Chem. 44 , 199-267, (1988)

 Synonyms

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine
MFCD00191918
Pyridine, 3-chloro-2-fluoro-5-(trifluoromethyl)-
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