Quinpirole dihydrochloride

Modify Date: 2024-01-09 07:03:10

Quinpirole dihydrochloride Structure
Quinpirole dihydrochloride structure
Common Name Quinpirole dihydrochloride
CAS Number 73625-62-4 Molecular Weight 255.78700
Density N/A Boiling Point N/A
Molecular Formula C13H22ClN3 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Quinpirole dihydrochloride


rel-Quinpirole (rel-LY 141865) dihydrochloride, an ergot compound, is a selective dopamine (DA) D2 receptor agonist. rel-Quinpirole dihydrochloride can be used for research on neurological diseases[1].

 Names

Name (-)-quinpirole hydrochloride
Synonym More Synonyms

 Quinpirole dihydrochloride Biological Activity

Description rel-Quinpirole (rel-LY 141865) dihydrochloride, an ergot compound, is a selective dopamine (DA) D2 receptor agonist. rel-Quinpirole dihydrochloride can be used for research on neurological diseases[1].
Related Catalog
References

[1]. X T Hu, et al. Disinhibition of nucleus accumbens neurons by the dopamine D2 receptor agonist LY-141865: prevented by 6-OHDA pretreatment. Brain Res. 1988 Mar 22;444(2):389-93.  

 Chemical & Physical Properties

Molecular Formula C13H22ClN3
Molecular Weight 255.78700
Exact Mass 255.15000
PSA 31.92000
LogP 2.73880

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles6

More Articles
Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae.

J. Neurosci. 31 , 5512-25, (2011)

An imbalance in dopamine-mediated neurotransmission is a hallmark physiological feature of neuropsychiatric disorders, such as schizophrenia. Recent evidence demonstrates that dopamine D(2) receptors,...

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.

Hum. Mol. Genet. 24(7) , 1929-44, (2015)

The essential micronutrient manganese is enriched in brain, especially in the basal ganglia. We sought to identify neuronal signaling pathways responsive to neurologically relevant manganese levels, a...

Biphasic effect of D-2 agonist quinpirole on locomotion and movements.

Eur. J. Pharmacol. 161 , 151-157, (1989)

The effects of the D-2 agonist quinpirole on forward progression, and on vertical and lateral movements, were measured for 2 h in rats injected with either saline, 0.03, 0.125, 0.5 or 8 mg/kg of the d...

 Synonyms

(+/-)-quinpirole dihydrochloride
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