(±)-盐酸喹吡罗

更新时间：2025-08-27 02:50:28

(±)-盐酸喹吡罗结构式	常用名	(±)-盐酸喹吡罗	英文名	Quinpirole dihydrochloride
	CAS号	73625-62-4	分子量	255.78700
	密度	N/A	沸点	N/A
	分子式	C₁₃H₂₂ClN₃	熔点	N/A
	MSDS	美版	闪点	N/A

(±)-盐酸喹吡罗用途

rel-Quinpirole (rel-LY 141865) dihydrochloride 是一种麦角化合物,是一种选择性多巴胺 D2 受体激动剂。rel-Quinpirole dihydrochloride 可用于神经系统疾病的研究。

中文名	(±)-盐酸喹吡罗
英文名	(-)-quinpirole hydrochloride
英文别名	更多

描述	rel-Quinpirole (rel-LY 141865) dihydrochloride 是一种麦角化合物,是一种选择性多巴胺 D2 受体激动剂。rel-Quinpirole dihydrochloride 可用于神经系统疾病的研究。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体信号通路 >> 神经信号通路 >> 多巴胺受体研究领域 >> 神经疾病
参考文献	[1]. X T Hu, et al. Disinhibition of nucleus accumbens neurons by the dopamine D2 receptor agonist LY-141865: prevented by 6-OHDA pretreatment. Brain Res. 1988 Mar 22;444(2):389-93.

分子式	C₁₃H₂₂ClN₃
分子量	255.78700
精确质量	255.15000
PSA	31.92000
LogP	2.73880
InChIKey	GJIGRGIGKHPYTK-LWCZFAHISA-N
SMILES	CCCN1CCCC2Cc3[nH]ncc3CC21.Cl.Cl

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport

Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae.

J. Neurosci. 31 , 5512-25, (2011)

An imbalance in dopamine-mediated neurotransmission is a hallmark physiological feature of neuropsychiatric disorders, such as schizophrenia. Recent evidence demonstrates that dopamine D(2) receptors,...

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.

Hum. Mol. Genet. 24(7) , 1929-44, (2015)

The essential micronutrient manganese is enriched in brain, especially in the basal ganglia. We sought to identify neuronal signaling pathways responsive to neurologically relevant manganese levels, a...

Biphasic effect of D-2 agonist quinpirole on locomotion and movements.

Eur. J. Pharmacol. 161 , 151-157, (1989)

The effects of the D-2 agonist quinpirole on forward progression, and on vertical and lateral movements, were measured for 2 h in rats injected with either saline, 0.03, 0.125, 0.5 or 8 mg/kg of the d...

(+/-)-quinpirole dihydrochloride