Isolimonexic acid
Modify Date: 2024-01-02 16:56:23
Isolimonexic acid structure
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Common Name | Isolimonexic acid | ||
|---|---|---|---|---|
| CAS Number | 73904-93-5 | Molecular Weight | 502.510 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 788.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C26H30O10 | Melting Point | 315-316℃ | |
| MSDS | N/A | Flash Point | 270.0±26.4 °C | |
Use of Isolimonexic acidIsolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1]. |
| Name | (4aS,6aR,8aR,8bR,9aS,12R,12aS,14aR,14bR)-12-(5-hydroxy-2-oxo-2,5-dihydrofuran-3-yl)-6,6,8a,12a-tetramethyldecahydro-1H,3H-oxireno[2,3-d]pyrano[4',3':3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione |
|---|---|
| Synonym | More Synonyms |
| Description | Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1]. |
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| Related Catalog | |
| Target |
IC50: 25.60 μM (aromatase)[1] |
| In Vitro | Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines[1]. Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 788.3±60.0 °C at 760 mmHg |
| Melting Point | 315-316℃ |
| Molecular Formula | C26H30O10 |
| Molecular Weight | 502.510 |
| Flash Point | 270.0±26.4 °C |
| Exact Mass | 502.183899 |
| PSA | 137.96000 |
| LogP | -0.84 |
| Vapour Pressure | 0.0±6.2 mmHg at 25°C |
| Index of Refraction | 1.621 |
| Hazard Codes | Xi |
|---|
| 1H,3H-Oxireno[c]pyrano[4'',3'':2',3']furo[3',4':5,6]naphtho[1,2-d]pyran-3,8,10(6H,9aH)-trione, 12-(2,5-dihydro-5-hydroxy-2-oxo-3-furanyl)decahydro-6,6,8a,12a-tetramethyl-, (4aS,6aR,8aR,8bR,9aS,12R,12aS,14aR,14bR)- |
| (4aS,6aR,8aR,8bR,9aS,12R,12aS,14aR,14bR)-12-(5-Hydroxy-2-oxo-2,5-dihydro-3-furanyl)-6,6,8a,12a-tetramethyldecahydro-3H-oxireno[d]pyrano[4',3':3,3a][2]benzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione |