ACV 1

Modify Date: 2024-01-04 11:22:08

ACV 1 Structure
ACV 1 structure
Common Name ACV 1
CAS Number 740980-24-9 Molecular Weight 1806.98000
Density N/A Boiling Point N/A
Molecular Formula C71H103N23O25S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ACV 1


ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. ACV1 is ~100-fold less potent on human α9α10 vs. rat nAChRs[1].

 Names

Name acv 1
Synonym More Synonyms

 ACV 1 Biological Activity

Description ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. ACV1 is ~100-fold less potent on human α9α10 vs. rat nAChRs[1].
Related Catalog
Target

IC50: 19 nM (α9α10 nAChR), 140 nM (α6/α3β2β3), 980 nM (α6/α3β4)[1]

References

[1]. J Michael McIntosh, et al. Alpha9 nicotinic acetylcholine receptors and the treatment of pain. Biochem Pharmacol. 2009 Oct 1;78(7):693-702.  

 Chemical & Physical Properties

Molecular Formula C71H103N23O25S4
Molecular Weight 1806.98000
Exact Mass 1805.64000
PSA 875.26000

 Synonyms

gly-cys-cys-ser-asp-pro-arg-cys-asn-tyr-asp-his-pro-glu-ile-cys-nh2