ACV 1

Modify Date: 2024-01-04 11:22:08

ACV 1 structure	Common Name	ACV 1
	CAS Number	740980-24-9	Molecular Weight	1806.98000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₁H₁₀₃N₂₃O₂₅S₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ACV 1

ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. ACV1 is ~100-fold less potent on human α9α10 vs. rat nAChRs[1].

Name	acv 1
Synonym	More Synonyms

Description	ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. ACV1 is ~100-fold less potent on human α9α10 vs. rat nAChRs[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	IC50: 19 nM (α9α10 nAChR), 140 nM (α6/α3β2β3), 980 nM (α6/α3β4)[1]
References	[1]. J Michael McIntosh, et al. Alpha9 nicotinic acetylcholine receptors and the treatment of pain. Biochem Pharmacol. 2009 Oct 1;78(7):693-702.

Molecular Formula	C₇₁H₁₀₃N₂₃O₂₅S₄
Molecular Weight	1806.98000
Exact Mass	1805.64000
PSA	875.26000

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