6-methyl-3-nitropyridin-2-ol

Modify Date: 2025-08-25 13:44:47

6-methyl-3-nitropyridin-2-ol Structure
6-methyl-3-nitropyridin-2-ol structure
Common Name 6-methyl-3-nitropyridin-2-ol
CAS Number 7464-14-4 Molecular Weight 154.123
Density 1.4±0.1 g/cm3 Boiling Point 334.2±37.0 °C at 760 mmHg
Molecular Formula C6H6N2O3 Melting Point 179 °C (dec.)(lit.)
MSDS Chinese Flash Point 155.9±26.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Hydroxy-5-methyl-3-nitropyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 334.2±37.0 °C at 760 mmHg
Melting Point 179 °C (dec.)(lit.)
Molecular Formula C6H6N2O3
Molecular Weight 154.123
Flash Point 155.9±26.5 °C
Exact Mass 154.037842
PSA 78.94000
LogP 0.15
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.605
InChIKey QAINEQVHSHARMD-UHFFFAOYSA-N
SMILES Cc1c[nH]c(=O)c([N+](=O)[O-])c1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

~63%

6-methyl-3-nitropyridin-2-ol Structure

6-methyl-3-nitr...

CAS#:7464-14-4

Literature: Beijing Yiling Bioengineering Co., Ltd. Patent: EP2366691 A1, 2011 ; Location in patent: Page/Page column 8-9 ;

~%

6-methyl-3-nitropyridin-2-ol Structure

6-methyl-3-nitr...

CAS#:7464-14-4

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 13 p. 3983 - 3987

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 6-methyl-3-nitropyridin-2-olBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

6-methyl-3-nitropyridin-2-ol
6-Methyl-3-nitropyridin-2(1H)-one
6-Methyl-3-nitro-2(1H)-pyridinone
2-Hydroxy-3-nitro-5-picoline
5-Methyl-3-nitro-2(1H)-pyridinone
MFCD02070021
5-methyl-3-nitropyridin-2-ol
6-Methyl-3-nitropyridin-2(1H)-on
2-Hydroxy-6-methyl-3-nitropyridine
5-methyl-3-nitro-1H-pyridin-2-one
3-(nitro)-5-methylpyridin-2-ol
5-Methyl-3-nitropyridin-2(1H)-one
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