(E)-10-Hydroxy Nortriptyline maleate

Modify Date: 2024-01-08 16:00:55

(E)-10-Hydroxy Nortriptyline maleate Structure
(E)-10-Hydroxy Nortriptyline maleate structure
Common Name (E)-10-Hydroxy Nortriptyline maleate
CAS Number 74853-74-0 Molecular Weight 395.44800
Density N/A Boiling Point N/A
Molecular Formula C23H25NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (E)-10-Hydroxy Nortriptyline maleate


(E)-10-Hydroxy Nortriptyline maleate is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

 Names

Name (Z)-but-2-enedioic acid,(11E)-11-[3-(methylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
Synonym More Synonyms

 (E)-10-Hydroxy Nortriptyline maleate Biological Activity

Description (E)-10-Hydroxy Nortriptyline maleate is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
Related Catalog
References

[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

[2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

 Chemical & Physical Properties

Molecular Formula C23H25NO5
Molecular Weight 395.44800
Exact Mass 395.17300
PSA 106.86000
LogP 3.42000

 Synonyms

trans-10-Hydroxy Nortriptyline Maleate