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47132-16-1

47132-16-1 structure
47132-16-1 structure
  • Name: (E)-10-Hydroxynortriptyline
  • Chemical Name: ()-trans-10-hydroxynortriptyline
  • CAS Number: 47132-16-1
  • Molecular Formula: C19H21NO
  • Molecular Weight: 279.37600
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2017-03-03 06:25:58
  • Modify Date: 2024-01-18 22:37:48
  • (E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

Name ()-trans-10-hydroxynortriptyline
Synonyms E-10-hydroxynortriptyline
trans-10-Hydroxy Nortriptyline Maleate
Description (E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
Related Catalog
References

[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8.

[2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

Density 1.164g/cm3
Boiling Point 462.3ºC at 760mmHg
Molecular Formula C19H21NO
Molecular Weight 279.37600
Flash Point 142.1ºC
Exact Mass 279.16200
PSA 32.26000
LogP 3.70820

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47132-16-1 structure

47132-16-1

Literature: Jean-Claude; Just Synthetic Communications, 1994 , vol. 24, # 11 p. 1565 - 1573

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47132-16-1 structure

47132-16-1

Literature: Jean-Claude; Just Synthetic Communications, 1994 , vol. 24, # 11 p. 1565 - 1573

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47132-16-1 structure

47132-16-1

Literature: Lassen; Perregaard 1983 , vol. 37, # 4 B p. 335 - 340

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47132-16-1 structure

47132-16-1

Literature: Lassen; Perregaard 1983 , vol. 37, # 4 B p. 335 - 340

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47132-16-1 structure

47132-16-1

Literature: Lassen; Perregaard 1983 , vol. 37, # 4 B p. 335 - 340

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47132-16-1 structure

47132-16-1

Literature: Lassen; Perregaard 1983 , vol. 37, # 4 B p. 335 - 340

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47132-16-1 structure

47132-16-1

Literature: Lassen; Perregaard 1983 , vol. 37, # 4 B p. 335 - 340

~%

47132-16-1 structure

47132-16-1

Literature: Lassen; Perregaard 1983 , vol. 37, # 4 B p. 335 - 340

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47132-16-1 structure

47132-16-1

Literature: Masubuchi, Yasuhiro; Iwasa, Takashi; Fujita, Shoichi; Suzuki, Tokuji; Horie, Toshiharu; Narimatsu, Shizuo Journal of Pharmacy and Pharmacology, 1996 , vol. 48, # 9 p. 925 - 929