47132-16-1

47132-16-1 structure

Name: (E)-10-Hydroxynortriptyline
Chemical Name: ()-trans-10-hydroxynortriptyline
CAS Number: 47132-16-1
Molecular Formula: C₁₉H₂₁NO
Molecular Weight: 279.37600
Catalog: Research Areas Neurological Disease
Create Date: 2017-03-03 06:25:58
Modify Date: 2025-08-25 12:06:24
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].

Name	()-trans-10-hydroxynortriptyline
Synonyms	E-10-hydroxynortriptyline trans-10-Hydroxy Nortriptyline Maleate

Description	(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline (HY-B1417). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8. [2]. Shimoda K, et al. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

156458-95-6

74-89-5

~91%

47132-16-1

Literature: Jean-Claude; Just Synthetic Communications, 1994 , vol. 24, # 11 p. 1565 - 1573

37439-92-2

47132-16-1

Literature: Jean-Claude; Just Synthetic Communications, 1994 , vol. 24, # 11 p. 1565 - 1573