monochloroethane

Modify Date: 2026-06-29 17:21:28

monochloroethane structure	Common Name	monochloroethane
	CAS Number	75-00-3	Molecular Weight	64.514
	Density	0.9±0.1 g/cm3	Boiling Point	12.7±3.0 °C at 760 mmHg
	Molecular Formula	C₂H₅Cl	Melting Point	−139 °C(lit.)
	MSDS	Chinese	Flash Point	-56.7±2.8 °C
	Symbol	GHS02, GHS07, GHS08	Signal Word	Danger

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	chloroethane
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	0.9±0.1 g/cm3
Boiling Point	12.7±3.0 °C at 760 mmHg
Melting Point	−139 °C(lit.)
Molecular Formula	C₂H₅Cl
Molecular Weight	64.514
Flash Point	-56.7±2.8 °C
Exact Mass	64.007980
LogP	1.50
Vapour density	2.22 (vs air)
Vapour Pressure	1169.9±0.0 mmHg at 25°C
Index of Refraction	1.362
InChIKey	HRYZWHHZPQKTII-UHFFFAOYSA-N
SMILES	CCCl
Stability	Stable. Highly flammable - may form explosive mixtures with air. Incompatible with strong oxidizing agents, alkali metals and their alloys.

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

monochloroethane MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH7525000

CHEMICAL NAME :: Ethane, chloro-

CAS REGISTRY NUMBER :: 75-00-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 56

MOLECULAR FORMULA :: C2-H5-Cl

MOLECULAR WEIGHT :: 64.52

WISWESSER LINE NOTATION :: G2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 152 gm/m3/2H

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Behavioral - general anesthetic Blood - hemorrhage

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 146 gm/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 40000 ppm/45M

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 19000 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 gm/m3/2H/60D-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Immunological Including Allergic - decrease in cellular immune response

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 570 mg/m3/4H/26W-I

TOXIC EFFECTS :: Liver - liver function tests impaired Immunological Including Allergic - decrease in cellular immune response Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5000 ppm/23H/11D-I

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19000 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15000 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15000 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - uterine tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 60 mg/m3/4H

SEX/DURATION :: male 26 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 322,33,1994 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 264 mg/m3 (100 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,315,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,315,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,315,1991 TOXICOLOGY REVIEW AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 40(3),A46,1979 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1000 ppm (2600 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,106,1971 OSHA PEL (Gen Indu):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 1000 ppm (2600 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-BELGIUM:TWA 1000 ppm (2640 mg/m3) JAN 1993 OEL-DENMARK:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-FINLAND:TWA 500 ppm (1300 mg/m3);STEL 625 ppm (1625 mg/m3) JAN 1993 OEL-FRANCE:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-GERMANY:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-HUNGARY:TWA 100 mg/m3;STEL 300 mg/m3 JAN 1993 OEL-JAPAN:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-POLAND:TWA 200 mg/m3 JAN 1993 OEL-RUSSIA:TWA 1000 ppm;STEL 50 mg/m3 JAN 1993 OEL-SWEDEN:TWA 500 ppm (1300 mg/m3);STEL 700 ppm (1900 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-TURKEY:TWA 1000 ppm (2600 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1000 ppm (2600 mg/m3);STEL 1250 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MONOCHLOROETHANE-air:Handle with caution REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 31970 No. of Facilities: 6154 (estimated) No. of Industries: 80 No. of Occupations: 66 No. of Employees: 96531 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 31970 No. of Facilities: 766 (estimated) No. of Industries: 12 No. of Occupations: 47 No. of Employees: 49210 (estimated) No. of Female Employees: 35368 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H315-H351
Supplemental HS	May form explosive peroxides., Repeated exposure may cause skin dryness or cracking.
Precautionary Statements	P210-P281
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes	F+:Extremelyflammable;Xn:Harmful;
Risk Phrases	R12;R40;R52/53
Safety Phrases	S9-S16-S33-S36/37-S61-S45-S7-S29-S36/37/39-S26-S53
RIDADR	UN 1993 3/PG 2
WGK Germany	2
RTECS	KH7525000
Hazard Class	2.1
HS Code	2903110000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 9
CAS#:64-17-5 Ethanol CAS#:87463-00-1 O-ethyl N-methy... CAS#:74-96-4 Bromoethane CAS#:141-78-6 ethyl acetate
CAS#:65039-09-0 1-Ethyl-3-methy... CAS#:60-29-7 Diethyl ether CAS#:103-80-0 Phenylacetyl ch... CAS#:93-89-0 Ethyl benzoate
CAS#:75-03-6 Ethyl iodide
DownStream 10
CAS#:105-93-1 N-ethylbis(2-et... CAS#:24426-21-9 1,2-Ethanediami... CAS#:4432-87-5 N-ethyl-N'-[2-(... CAS#:137554-10-0 N'-[2-(ethylami...
CAS#:5336-57-2 2-Ethyl-2-pheny... CAS#:3264-67-3 TRIETHYLOXONIUM... CAS#:557-66-4 Ethylamine hydr... CAS#:5668-93-9 3-Ethylbiphenyl
CAS#:699-91-2 2-Hydroxy-3-met... CAS#:488-17-5 3-Methylcatechol

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2903110000
Summary	2903110000 chloroethane。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:5.5%。General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

Eur. J. Med. Chem. 43 , 714-40, (2008)

Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org...

Identification of Dehalobacter reductive dehalogenases that catalyse dechlorination of chloroform, 1,1,1-trichloroethane and 1,1-dichloroethane.

Philos. Trans. R. Soc. Lond., B, Biol. Sci. 368(1616) , 20120318, (2013)

Two novel reductive dehalogenases (RDases) that are highly similar to each other but catalyse distinct dechlorination reactions were identified from Dehalobacter-containing mixed cultures. These two R...

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above u...

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

ethyl cerotate

Hexacosansaeure-aethylester

monochloroethane

1-CHLORO-ETHANE

hydrochloric ether

Ethylhexacosanoat

Chloroethane

ethyl chloride

1-ethyl chloride

mono-chloroethane

hexacosanoic acid ethyl ester

MFCD00000961

ETHYL HEXACOSANATE

EINECS 200-830-5

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the upstream materials of chloroethane?

A: Related upstream materials(CAS) of chloroethane: 64-17-5;87463-00-1;74-96-4;141-78-6;65039-09-0;60-29-7;103-80-0;93-89-0;75-03-6.

Q: What is the melting point of chloroethane?

A: Melting point of chloroethane is −139 °C(lit.).

Q: What is the molecular weight of chloroethane?

A: Molecular weight of chloroethane is 64.514.

Q: What is the molecular formula of chloroethane?

A: Molecular formula of chloroethane is C2H5Cl.

Q: What are the downstream products of chloroethane?

A: Related downstream products(CAS) of chloroethane: 105-93-1;24426-21-9;4432-87-5;137554-10-0;5336-57-2;3264-67-3;557-66-4;5668-93-9;699-91-2;488-17-5.

Q: What is the InChIKey of chloroethane?

A: InChIKey of chloroethane is HRYZWHHZPQKTII-UHFFFAOYSA-N.

Q: What is the LogP of chloroethane?

A: LogP of chloroethane is 1.50.

Q: What is the safety information for chloroethane?

A: Safety information for chloroethane: S9-S16-S33-S36/37-S61-S45-S7-S29-S36/37/39-S26-S53.

Q: What English synonyms does chloroethane have?

A: English synonyms of chloroethane: ethyl cerotate, Hexacosansaeure-aethylester, monochloroethane, 1-CHLORO-ETHANE, hydrochloric ether, Ethylhexacosanoat, Chloroethane, ethyl chloride, 1-ethyl chloride, mono-chloroethane, hexacosanoic acid ethyl ester, MFCD00000961, ETHYL HEXACOSANATE, EINECS 200-830-5.

Q: What is the boiling point of chloroethane?

A: Boiling point of chloroethane is 12.7±3.0 °C at 760 mmHg.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: monochloroethane
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Chloroethane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: chloroethane
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Chemical & Physical Properties

MSDS

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

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monochloroethane | FAQ

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