3'-fluoro-3'-deoxyadenosine

Modify Date: 2024-01-08 16:03:03

3'-fluoro-3'-deoxyadenosine Structure
3'-fluoro-3'-deoxyadenosine structure
Common Name 3'-fluoro-3'-deoxyadenosine
CAS Number 75059-22-2 Molecular Weight 269.23
Density N/A Boiling Point 628.6°C at 760 mmHg
Molecular Formula C10H12FN5O3 Melting Point N/A
MSDS N/A Flash Point 334°C

 Use of 3'-fluoro-3'-deoxyadenosine


3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol
Synonym More Synonyms

 3'-fluoro-3'-deoxyadenosine Biological Activity

Description 3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Boiling Point 628.6°C at 760 mmHg
Molecular Formula C10H12FN5O3
Molecular Weight 269.23
Flash Point 334°C
Exact Mass 269.09200
PSA 119.31000

 Synonyms

3'-F-dA
3'-Deoxy-3'-fluoroadenosine
3'-Fluoro-3'-deoxyadenosine
Adenosine,3'-deoxy-3'-fluoro