Anticonvulsant agent 2

Modify Date: 2024-01-29 16:49:18

Anticonvulsant agent 2 Structure
Anticonvulsant agent 2 structure
Common Name Anticonvulsant agent 2
CAS Number 75220-84-7 Molecular Weight 332.83
Density N/A Boiling Point N/A
Molecular Formula C21H17ClN2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anticonvulsant agent 2


Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity[1].

 Names

Name 4-(4-chlorophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine

 Anticonvulsant agent 2 Biological Activity

Description Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity[1].
Related Catalog
In Vivo Anticonvulsant agent 2 (compound10 a; 50 mg/kg, p.o.) 降低大鼠运动活性,抑制率为 21.01%[1]。 Anticonvulsant agent 2 (50 mg/kg; p.o.) 显示出抗癫痫活性,对大鼠的抑制率为24.45%[1]。 Animal Model: 180-250g, male Wistar rats[1] Dosage: 50 mg/kg Administration: P.o. Result: Showed antiepileptic activity with the inhibition rate of 24.45%.
References

[1]. Verma R, et al. Design, synthesis and neuropharmacological evaluation of new 2,4-disubstituted-1,5-benzodiazepines as CNS active agents. Bioorg Chem. 2020 Aug;101:104010.  

 Chemical & Physical Properties

Molecular Formula C21H17ClN2
Molecular Weight 332.83
Exact Mass 332.10800
PSA 24.39000
LogP 5.59130

 Synthetic Route

~90%

Anticonvulsant agent 2 Structure

Anticonvulsant ...

CAS#:75220-84-7

Literature: Du, Yuying; Tian, Fuli Journal of Chemical Research, 2006 , # 8 p. 486 - 489

~59%

Anticonvulsant agent 2 Structure

Anticonvulsant ...

CAS#:75220-84-7

Literature: Orlov, V. D.; Kolos, N. N.; Yaremenko, F. G.; Lavrushin, V. F. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 5 p. 547 - 550 Khimiya Geterotsiklicheskikh Soedinenii, 1980 , # 5 p. 697 - 700

~%

Anticonvulsant agent 2 Structure

Anticonvulsant ...

CAS#:75220-84-7

Literature: Verma, Anil K.; Koul, Summon; Razdan, Tej K.; Kapoor, Kamal K. Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1064 - 1073

~%

Anticonvulsant agent 2 Structure

Anticonvulsant ...

CAS#:75220-84-7

Literature: Verma, Anil K.; Koul, Summon; Razdan, Tej K.; Kapoor, Kamal K. Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1064 - 1073
Top Suppliers:I want be here

No recommended suppliers.

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3