SSR125543

Modify Date: 2025-08-22 17:15:01

SSR125543 Structure
SSR125543 structure
Common Name SSR125543
CAS Number 752253-39-7 Molecular Weight 483.04000
Density N/A Boiling Point N/A
Molecular Formula C27H28ClFN2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SSR125543


Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].

 Names

Name 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine

 SSR125543 Biological Activity

Description Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].
Related Catalog
Target

IC50: CRF1 receptor

References

[1]. Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst).

 Chemical & Physical Properties

Molecular Formula C27H28ClFN2OS
Molecular Weight 483.04000
Exact Mass 482.15900
PSA 53.60000
LogP 7.51740
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