CHAPS

Modify Date: 2024-01-03 11:29:02

CHAPS structure	Common Name	CHAPS
	CAS Number	75621-03-3	Molecular Weight	614.877
	Density	1.01 g/mL at 20ºC	Boiling Point	N/A
	Molecular Formula	C₃₂H₅₈N₂O₇S	Melting Point	156-158ºC
	MSDS	Chinese	Flash Point	N/A

Use of CHAPS

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. Target: CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons.CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions and is electrically neutral. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.

Name	3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate
Synonym	More Synonyms

Description	CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. Target: CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons.CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions and is electrically neutral. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
References	[1]. Ofri D, Ritter AM, Liu YF et al. Characterization of solubilized opioid receptors: reconstitution and uncoupling of guanine nucleotide-sensitive agonist binding. J Neurochem. 1992 Feb;58(2):628-35. [2]. Banerjee P, Joo JB, Buse JT, Dawson G. Differential solubilization of lipids along with membrane proteins by different classes of detergents. Chem Phys Lipids. 1995 Aug 1;77(1):65-78. [3]. Pasquali C, Fialka I, Huber LA. Preparative two-dimensional gel electrophoresis of membrane proteins. Electrophoresis. 1997 Dec;18(14):2573-81. [4]. Menshikova I, Menshikov E, Filenko N, Lyubchenko YL. Nucleosomes structure and dynamics: effect of CHAPS. Int J Biochem Mol Biol. 2011;2(2):129-137. [5]. Krofli? A, Sarac B, Be?ter-Roga? M. Thermodynamic characterization of 3-[(3-cholamidopropyl)-dimethylammonium]-1-propanesulfonate (CHAPS) micellization using isothermal titration calorimetry: temperature, salt, and pH dependence. Langmuir. 2012 Jul 17;28(

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Others

References

[1]. Ofri D, Ritter AM, Liu YF et al. Characterization of solubilized opioid receptors: reconstitution and uncoupling of guanine nucleotide-sensitive agonist binding. J Neurochem. 1992 Feb;58(2):628-35.

[2]. Banerjee P, Joo JB, Buse JT, Dawson G. Differential solubilization of lipids along with membrane proteins by different classes of detergents. Chem Phys Lipids. 1995 Aug 1;77(1):65-78.

[3]. Pasquali C, Fialka I, Huber LA. Preparative two-dimensional gel electrophoresis of membrane proteins. Electrophoresis. 1997 Dec;18(14):2573-81.

[4]. Menshikova I, Menshikov E, Filenko N, Lyubchenko YL. Nucleosomes structure and dynamics: effect of CHAPS. Int J Biochem Mol Biol. 2011;2(2):129-137.

[5]. Krofli? A, Sarac B, Be?ter-Roga? M. Thermodynamic characterization of 3-[(3-cholamidopropyl)-dimethylammonium]-1-propanesulfonate (CHAPS) micellization using isothermal titration calorimetry: temperature, salt, and pH dependence. Langmuir. 2012 Jul 17;28(

Density	1.01 g/mL at 20ºC
Melting Point	156-158ºC
Molecular Formula	C₃₂H₅₈N₂O₇S
Molecular Weight	614.877
Exact Mass	614.396484
PSA	155.37000
LogP	-4.32
Index of Refraction	1.6900 (estimate)
Storage condition	2-8°C
Stability	Moisture Sensitive: Hydroscopic
Water Solubility	H2O: 50 mg/mL at 20 °C, clear, colorless \| Soluble in water (10 mg/ml). Soluble in DMF and hot methanol.

CHAPS MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation.

Biochem. Pharmacol. 90(3) , 288-96, (2014)

Inhibition of 17α-hydroxylase/17,20-lyase (CYP17), which dictates the proceeding of androgen biosynthesis, is recommended as an effective treatment for androgen-dependent diseases. However, androgen d...

Endogenous fatty acids in olfactory hairs influence pheromone binding protein structure and function in Lymantria dispar.

Arch. Biochem. Biophys. 579 , 73-84, (2015)

The gypsy moth utilizes a pheromone, (7R,8S)-2-methyl-7,8-epoxyoctadecane, for mate location. The pheromone is detected by sensory hairs (sensilla) on the antennae of adult males. Sensilla contain the...

A biophysical study on molecular physiology of the uncoupling proteins of the central nervous system.

Biosci. Rep. 35 , (2015)

Mitochondrial inner membrane uncoupling proteins (UCPs) facilitate transmembrane (TM) proton flux and consequently reduce the membrane potential and ATP production. It has been proposed that the three...

3-[Dimethyl(3-{[(3α,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]propane-1-sulfonate

CHAPS,HighPurity

3-[Dimethyl(3-{[(3α,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]-1-propanesulfonate

1-Propanaminium, N,N-dimethyl-3-sulfo-N-[3-[[(3α,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]propyl]-, inner salt

3-{Dimethyl[3-({(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)propyl]ammonio}-1-propanesulfonate

CHAPS Solution

CHAPS ELECTROPHORESIS REAGENT

1-Propanaminium, N,N-dimethyl-3-sulfo-N-[3-[[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]propyl]-, inner salt

MFCD00012116

CHAPS-SOL GRADE

3-[Dimethyl(3-{[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]-1-propanesulfonate

CHAPS

3-[Dimethyl(3-{[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]propan-1-sulfonat

1-Propanaminium, N,N-dimethyl-3-sulfo-N-[3-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]propyl]-, inner salt

3-[Dimethyl(3-{[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]-1-propanesulfonate

3-[Dimethyl(3-{[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]propane-1-sulfonate

CHAPS extrapure

TREND

N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium Hydroxide Inner Salt

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: CHAPS
Price: ￥175.0/5g ￥555.0/25g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: CHAPS
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU-CHEM_3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate 75621-03-3
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

Get all suppliers and price by the below link:

CHAPS suppliers

Price: ￥50/250mg

Reference only. check more CHAPS price

CHAPS

Use of CHAPS

Names

CHAPS Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Customs

Articles77

Synonyms