2,2,3,3-Tetrafluoro-1-propanol

Modify Date: 2024-01-02 11:28:20

2,2,3,3-Tetrafluoro-1-propanol Structure
2,2,3,3-Tetrafluoro-1-propanol structure
Common Name 2,2,3,3-Tetrafluoro-1-propanol
CAS Number 76-37-9 Molecular Weight 132.057
Density 1.4±0.1 g/cm3 Boiling Point 109.5±0.0 °C at 760 mmHg
Molecular Formula C3H4F4O Melting Point -15°C
MSDS Chinese USA Flash Point 31.0±25.9 °C
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

 Names

Name 2,2,3,3-Tetrafluoro-1-propanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 109.5±0.0 °C at 760 mmHg
Melting Point -15°C
Molecular Formula C3H4F4O
Molecular Weight 132.057
Flash Point 31.0±25.9 °C
Exact Mass 132.019821
PSA 20.23000
LogP 0.30
Vapour Pressure 13.1±0.4 mmHg at 25°C
Index of Refraction 1.296
Storage condition Flammables area
Stability Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, sodium, potassium, acid chlorides, acid anhydrides.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UB9400000
CHEMICAL NAME :
1-Propanol, 2,2,3,3-tetrafluoro-
CAS REGISTRY NUMBER :
76-37-9
BEILSTEIN REFERENCE NO. :
1738264
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C3-H4-F4-O
MOLECULAR WEIGHT :
132.07
WISWESSER LINE NOTATION :
Q1XFFYFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3400 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes
REFERENCE :
JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ Volume(issue)/page/year: 4,262,1962
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2000 ppm/4H
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness
REFERENCE :
JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ Volume(issue)/page/year: 4,262,1962
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8600 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,109,1982

 Safety Information

Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger
Hazard Statements H226-H319-H331
Precautionary Statements P261-P305 + P351 + P338-P311
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R10;R20;R36/37/38
Safety Phrases S26-S37/39-S16
RIDADR UN 1986 3/PG 3
WGK Germany 1
RTECS UB9400000
Packaging Group III
Hazard Class 3
HS Code 2905590090

 Synthetic Route

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2,2,3,3-Tetrafluoro-1-propanol Structure

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CAS#:76-37-9

Literature: US2002/86131 A1, ;

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2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: Krutikova; Krutikov; Erkin Russian Journal of General Chemistry, 2010 , vol. 80, # 3 p. 428 - 433

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2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: Paleta, O.; Dedek, V.; Reutschek, H.; Timpe, H.-J. Journal of Fluorine Chemistry, 1989 , vol. 42, p. 345 - 354

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2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: Industrial and Engineering Chemistry, , vol. 51, p. 829

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2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 30, # 7 p. 1332 - 1334 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 7 p. 1641 - 1643

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2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 2305 - 2309 Zhurnal Organicheskoi Khimii, , vol. 20, # 12 p. 2533 - 2539

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2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 51, # 3 p. 542 - 547,423 - 428

~%

2,2,3,3-Tetrafluoro-1-propanol Structure

2,2,3,3-Tetrafl...

CAS#:76-37-9

Literature: Russian Journal of General Chemistry, , vol. 80, # 3 p. 428 - 433

 Customs

HS Code 2905590090
Summary 2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles2

More Articles
Supercritical CO2 desorption of activated carbon loaded with 2,2,3,3-tetrafluoro-1-propanol in a rotating packed bed.

Environ. Sci. Technol. 42(6) , 2150-4, (2008)

Desorption of activated carbon loaded with 2,2,3,3-tetrafluoro-1-propanol (TFP) by supercritical carbon dioxide in a rotating packed bed was investigated in this study. The experimental data show that...

Mineralization and defluoridation of 2,2,3,3-tetrafluoro -1-propanol (TFP) by UV oxidation in a novel three-phase fluidized bed reactor (3P-FBR).

Water Res. 47(7) , 2325-30, (2013)

2,2,3,3-Tetrafluoro-1-propanol (TFP, C3H4F4O, M.W. = 132.06) is extensively used as the solvent in CD-R and DVD-R fabrication. Since it has a fluorinated alky-chain configuration and is non-biodegrada...

 Synonyms

1-Propanol, 2,2,3,3-tetrafluoro-
EINECS 200-955-5
2,2,3,3-Tetrafluoro-1-propanol
2,2,3,3-Tetrafluoro-1-propanol/TFP
2,2,3,3-tetrafluoropropan-1-ol
MFCD00004676
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